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Sport Medicine Ethics (2005, Stockholm)

Sport Medicine Ethics, Stockholm,May 2005-05-24

Christian Munthe Sport, Med and HC

HC goods -    securing certain lev of health (prevention, restoration, ailment) -    in a just way

SM goods – secure health conducive to athletic performance -    beyond HC lev ofhealth and goals, also enhancmenet not approach reqt of justive

dual influences of SM -    ethos of trad med (life and qual, autonomy, justice) -    ethos of sports (supreme performance and excellence), autonomy, fairness

Rationing HC -    HC: need paramount (and prognosis); prov for worse off upto a level; contested ideas about relevance of numbers;l contested ides about relevance of merit/desert -    SM: unclear about what is paramount; resource not limted by same funds; numbers probc; merit desert can work both ways (sports injuries, self inflicted, heroes benefit soc)

Conested procedures – 4 args (doping, etc)

1.    SM should adapt to ethos of HC (either prob: goals different; or: reason for revising 2.    HC adapt to ethos of Sports (excellence, fairness): either: prob: rules and goals of sport arbitrary from medical view, or: recom for breaking SM out of HC 3.    Sports should adapt to ethos of HC (but: safety or justice arg) 4.    HC should adapt to ethos of SM (safet, justice) Either: probc, due to dit; radical revision of HC

Remarks: -    what ethos is relevant for ethos of SM? -    ‘place’ of SM? -    Basic prob for ethos based ethics – virtue sport philosophy, or communitarian theories of justice -    Challenge for medical ethics – sm/sport -    There is no archimedian point -    Inquiries into concrete, partic issues needed

Claudio Tamburini

No difference view – between med everything and sport med ethics – latter only more specific applic of normative framework in med ethics generally – NOT TRUE – eg. Autonomy/privacy function/meaning in different way in sport – sport med more paternalistic – eg. Training technique – athletes are not protected -, must subit to rules, - testing = privacynot same – no difference view obviously wrong

But should they be different? – yes: athletes are not sick – wrong to giv medicine for sick – Lyjungqvist = doping is medicine – ‘athletes are healthy’ – thus athletes are not patients – not general rights of HC system  - what’s wrong w athletes using med (prov not state funded) – athlete are patients – meaning of patient – suffer from pathology – too narrow – today healthy people give treatment – not clear where to draw t line – healthy people already consume – WHO – well-being – dependence of medical prof for (non(athlete – exposure to effect of medicine makes vulnerable and this vuln indicates patient status , regardless of whether customer – athlete? – are patients – conclusion: recog as patient

ME: ethos of medicine is that absence of proof does not mean absence of reasonable expectation or evidence; cannot refer to WHO for support for an ethical view same for anti doping code

Anders Sandberg

Health consumerism – what are enhancement treatments? – alcohol caffeine, etc – st johns wort – ginseng – positive psych – beta blockers (musicians) – growth hormone – since it is an enhanceent(?) – IGF – improved elasticity – cognitive enhancement – social (prozac -= leadership) – acceptance is complex =- is morphological freedom a right? – functional food yes, GM less, but dfferes in culture – Japan 50%, would consider, 66% would for … therapy – Thaliand, India, yes, if adv – WHO – health as optimal but function relation to ones own cgoals – conclusion: doping and enhancement  - performance artists: how they change their body

ME: only medical intervention reqd ; modafinial, global GM same?

Question&A

JS: by allowing enhancement, implies coercion

MMc: autonomy – inc vulnerability = higher standard SH: sm goal fro physiocan as not ‘excelelnt’, but goal of employer – make sure team wins CL: health definition tooo wide – who – boorse – too narrow Tomas (athlete): paternalism – we let athlete do unhealthy things, so not too paternalistic – wada: not prov risk to health – Is pressure on autonomy so freat for an athlete? CT: as patient more exposed to med prof – athlete can choose not to expose themselves JP: beta-blockers not analogous – art and creaft

REF: MIGUEL NICOLELI – NEUROSCIENCE, CHIPS IN ARMS, MAGNETIC

Susan Sherwin

Should we welcome/resign/resist – social polic y or indiv choice? – Francoise Bayliss/ - oppose – to pursue GE = research prog – sports req different kinds of body type – enthusiasm for GE = popular reductionism – avoid enthusiasm welcome – also reject 2nd (resign) – beleief in efficacy will lead to demand (!) – resigned acceptance is self-fulfilling- reject inevitability – opt for resistance – social policy, not indiv choice – indiv choice: autonomy as informed choice – prog grants to challenge rights based – for some implices reduced autonomy – must include right to refuse – but in sport not possible – broader implic for young athletes – most likely to be applied in adolesecenc, this is bad time – cannot claim ‘iformned’ – challenge indiv – reject trad economy defences – reject indiv autonomy and personhood and supplement w relational theory – persns as partially contested by social relations – liberal theorie treat self-hood as indiv, relations -= selfhood as ongoing project – wht are t proceses by which a person holds certain prefers – fem theory – irrationality based on consensus (irrational to resist conformity – become irrational NOT to select enhancement – excellence as GM conveys something to those who are genetically deficitine – new expctation for improvement – entrenches legitimacy of comp (social Darwinism) – precautionaryu princip0le needed – excellence is not GM, but social programes – less sexy perhaps

ME: what else shouldn’t we have done based on this model?

Sarah Teeztsel

Adam Moore – unexamined life..open to inspection – proivacy and tech – gene doping – uise of legl gene theory for sport not acceptable – banning just -    drug testing in sport (Canada report) – invasion of privacy - acknowleged

Nick Bostrom

(w Toby Ord) – good or bad – double epistemic prob – 1. radical disagreement about conseqs, 2. Eval of consqs: even if we know what would happen, diffi to say whether, on balance, is good orbad – double epistemic chance of only major reform – eg implic of abolishing slavery, rely on stat and subj intuitions judgement – biases – ‘status quo’ bias – doc by exptl economits – defined as inapprop or irrational pref for state, just because it is XX – ‘mug’ experiment – choc bar or nice mug – predict that 50% would get what they wantede, but 90% choose to return item – ‘endowment’ effect – place value on something just because given to us – irrational? – but status quo bias clear explanation in bioethics, definition of judgmeent for this

how elminate bias? – hypothetical enhancement of cognitve (eg. Memory) – conseq: should we think enhancenment would have good/bad oconseqs? – oft doubts about this (fear of unknown) – how adjudicate between opposing views – ask counter intuitive: what if did opposite? – decrease human cognitive capacity – clearer agreement that bad – those who also bad must judge why ‘current’ level is optimal – burden of proof is on those who make these claims – seems implausible that isat peak – reversal test –doesn’t say is wrong, but that burden of proof on ‘status quo’ – cognitive enhancement: arg from ‘evol adaptation’ reg ratio of heart size to body size – w cognitive enhancements, arg doesn’t work, since eg enviro different now than was previously (ie now cognitive society, previously physical soc);  - if human cog cap corresponded w brain size, then might be good – preventing costs to bigger brain – now less – now less – what evol optimises, so inclusive fitness, but human sep side undermine this – eg. Intell – 2. Arg from transition costs: (do not sxXX, kust because implies t difficult – cost to great - - 3. Arg from risk – but this works both ways – riskness doesn’t imply anything specific -  cognitive benefits enormous – 4. Arg from ‘persons affecting’ – consier not likely to effect – 2nd reason of reversal – imagine – double reversal – more powerful heuristic – as takes into account these other args – toxin in water, reduce cog, intro therapy to water – then toxin removes, then cog enahncenemts above optimal (double reversal test) – reverswal and double reversal best comforts to status quo bias – it extent bias – must interpolate  2 versions of status quo – can take into account genesis choices , deontological considerations, and social policy – intuition about ‘natural ‘ prevalent in bioethics – natural = good – intuition about natural more properly about ‘status quo’

Mike McNamee Slippery Slope

Half-baked HN – witnessin convergence of system – no human or postmodern consition – but convergenet – views of transhumanism not clear – ‘transcend limits’ of HN is wrong – ‘features? Is more approp – reduce vulnerability to human – posthuman? – use to enahncene H choices – no need to shed HN, but augment – in favour: facilitate 2 aims: use technology to improve Hs – transhumanism: ‘ideal blue print’ – personhood: if indep of species, then moral status maintained – arg: 2 types of being|: human and posthuman – Buchanan et al: found on category of H – no longer common H – expand inequalities – genetically deficient – autonomy as RRATIONAL CHOICE THEORY – DEMOcratic technology is naïve and idealistic – surely coomerce will govern – in elite sport prevalent – double blind: poor pay for pleasure of envy – for other transhuman 0 engineer resistance – what is idal type? – criteria of THN – affront to morality – eg. HR, tranhusmanist might be beyond human – why moved by approach of ‘solidarity’ – life span: agening as a creapping evil – woody allen: ‘immortal not by doing great deeds, but by not dying’ – burden of proof should be on transhumanist – transhumanist has no limits and thi is a prob – eg. Bod transplant – burden of proof is on ‘us’ – t human is ‘repugnant (Kass) – proof of transhumanist (HE!) – misuse of drugs for sport enhancement – genetic enhancement – approach to therapy first and subjective normalise these – Kant’s ‘dove’ – preconditions of dyling – should celebrate human vulnerability

For NB : does arg depend on stable conseqs? Different versions of autonomy

Jared Diamond – h not changed much in thouse years, but h can find new ways of re-working hu  limits – intell  (rather acculating of cuilture allows more effective development )

Kate fox book – ‘what do we want, gradual chance, when do we want it, in due course’

NB: Asian disease prob –

600 will die without intervention

A  - 200 saved 75% B – 1/3 600 saved, 2/3 0 saved 28%

C 400 die 22% D 1/3 0 die, 2/3 600 die %78%

A and C are same

B and D are same People overweigh losses in decision making

JS: satuat quo not irrational -    if neither v good nor v bad, then not irrational -    - if chose for 150 age, but might me 40 yr, stick w 80 -    in absence of giving people choice to change, giv opp to do that o    if has rich, then prob not whether conformist – cosmetic surgery entrenches norms

Jim Parry –

Supplements – rusedski – defence – supplement – is suppleenmt controlled Different between an orange or taking vitamin pill – ME: an orange is more (still don’t really know what foos is) – foods are unknown ssubstances

Soren Holm -    new drugs – social position  - should not expect sports doctors to prov good advice -    no reason to beloieve that no ban would lead to open safer doping

should not pressure people finto taking big risks

sociall construction of rules – and arbitrariness of rules

MMc: autotelicity – have own rules

British Philosophy of Sport Association (2005)

BPSA2005 Conference Notes Sigmund Loland

From morals to medicine – a justification

DISPOSITION Why sport? T values of sport to t indiv and soc A selective, critical review of answers from the past and t current A sketch of a possible justification Some implications

MORALITY Arnold and muscular Christianity Coubertin’s ilympism Nansen: avoid sport and practice idrett – body culture of sports (or rather: skiing, the idrett of idretts) Camus: everything I know about ethics I’ve learned from sports

MORALITY II Doxa: sport is good! Children and youth sport -    a safe enviro -    sport as a tool in socialization elite sports -    the system -    the athlete

BUT Children’s sport and moral development (Bredemaier & Shields; Olweus) Elite sports and the society of the spectacle (Gebauer) The fascistoid roots of our admiration for sport heros (Tannsjo)

No obvious connection between sport and morality

How?

Prevalent ideas related to sport:

HEALTH I 1700s, French Encyclopedie (de Wachter) 1800s: t development of applied physiology and medicine (Hoberman) the workers’ sport movement of the mid war period (AIF) -    picked up idea of sport as health

HEALTH II WHO: overweight a global epidemic 1985-2004: av weight increase in adults +5-6kg 1993-2000: overweight 14yrs old from 7.5%-11.5% (Andersen et al, 2004) SDS: sedentary death syndrome

The hegemonic discourse

But… Crude instrumntalism and sociological naivete Individualization in a visual culture Medicalizartion (Zola, Waddington) Strong paternalism (hidden paternalism) ‘revenge of the body’

how?

Sport as a tool

Experiential qualities I Direct and sensual v win and lose Mastery and failure v cooperation and conflict Pleasure and pain v us and them

Experiential qualities II -    a concrete, embodied and sensual quest for answers to existential questions -    what can I/we do? What are my/our possibilities in time and space? What can i/we do as compared to others? Who am i/we?

Sport: testing out of our possibilities as embodied, sensual I’s

Normative anchoring -    Aristotelian eudaimonism: a holistic theory of ends -    Life as a web of values -    Neo-aristotelian virtue ethics (MacIntyre, McNamee) -    Standards of excellence – internal goods – virtues – moral virtue – the/a good life

CONCLUSION Morality and health as integrated values of variable significance Critique: high strung idealism versus practical knowledge Politics of justification and the unity and diversity of life

Could you imagine a version of boxing that did not fall prey to your sorts of concern – is it the ethos you reject or the activity -    critique is buying into the society of the spectacle thesis, rather than the activity

he is talking about the minds of people who watch

Mike McNamee

Polemical philosophy

‘human nature itself lies on the operating table, rdy for alteration, for eugenic and neuropsychic ‘enhancement’, for wholesale design. In leading laboratories, academic and industrial, new creators are condiently amassing their powers, while on the street their evangelists are zealously prophesying a posthuman future’ (Kass, L, 2002)

motivational set of technology intro -    baconian/Cartesian conceptions of science and its powers -    to question their instantation in a new modern ideology ‘transhumanism’sport medicines, genetics and t ‘enhancement’ ideology -    which Prometheus? Hesoid versus Aeschylus -    from athletic to medical hubris (mortality & Mortality)

technology to control nature -    ME: THIS IS NOT THE WAY THEORISTS OF Philosophy AND TECHNOLOGY ARTICULATE TECHNOLOGY

Nuances of myths of Prometheus – lens for hubris of genetic medicine -

science after bacon -    obsession w physical perfectioniams arises as a moral imperative, as sociologists of body have noted, w increasing pervasiveness of modern technology. Roots oder -    Bacon and Descarte emerges t impulse not merely to describe mechanically t operation of nature, but to control it

Moral topography -    Charles Taylor on moral sources of modern identity -    In sport med, might be about drawing relief, natural and artif of work of scientists therein -    As a metaphor for what I take to be t natural work of medicine in the relief of suffering and t artificiality of perf enhancement or t augmentation of natural abilities as opposed to t tradl therapeutic role of medicine

Physicians often sucked into ‘enhancement’

Nature and purposes of medicine hotly contested Roots in healing tradition Assist in presence of someone who suffers Telos of medicine This is lost to sports medicine

Kass’ classification of biomedical technology -    control of death and life -    control of human potentialities -    control of human achievements -    Kass, L.. (1985, 19-24) -    IVF – redefines life and death (not for this paper – ME: YES IT IS!)

Control of human potentialities

Genetic engineering wields 2 powers not shared by medical practice 1.    medicine treats exiting indivs and corrects deviations from health norms 2.    genetic engineering promises alterations to future generations (germ line therapy) and may create new capacities (hence new norms of health/fitness)

ME: HE PRESENTS A CRITIQUE ON GERMLINE ONLY

Changing germline is new.  – ME: NOT REALLY

Not merely to restore, but to augment -    ME: MEDICINE ALWAYS AUGMENTS

Contrl of human capacities -    the limits of many capacities and powers of an idiv are indeed genetically determined, but t nurturing and perfection of these capacities depends upon other influences’ (Kass, 23) (eg. Neurological and psychological manipulation -    ‘from its inception, modern science has been especially interested in finding reliable biological means-means more effective than exhortation or praise or blame-to attain t ends of sensible, decent, human conduct and peace of mind’ (ibid)

new ethics for new  biology. But not sure -    ME: WHEN PEOPPLE ARGUE THIS, THEY DO NOT MEAN THAT WE NEED NEW WAYS OF DOING ETHICS, OR NEW THEORISTS, BUT THAT THE RELATIONSHIPS UPON WHICH ETHICS ARE PREMISED, PARTIC IN MEDICINE, HAVE CHANGED. ALBERT JONSEN’S CASUISTRY, TOD CHAMBERS ‘NARRATIVE’ - New biology: old ethics -    Edelstein (1967: 357-9) notes t ancient greek philosophers task of undermining t glorification of t body -    McKenny cites pplat’s questions in t Republic when..

Plato’s questions -    how much attention should we dvote t our bodies in t effort to optimize our capacities? -    How much control should? -    What endsw? -    What limits …remove causes of suffering?

Scientist – reductionism -    ME: CANNOT ARGUE THIS.

New biology: new ethics? -    ideology – transhumanism -    strong transhumanism – -    weak transhumanism – human nature is a half-baked project o    no respect for sanctity of life

Sports medicine and scientism -    formerly when religion was storng and science weak, men mistook magic for medicine; now, when science is strong and religion weak,

anti-ageing main concern -    we should shed human nature -    taylor ‘we are vulnerable’ -    we should do everything we can to stop it

ME: critique of sci fi!?

Concern about ‘ideal blueprint’

Habermas, jonas, kass, macintryre,

ME: chris gray – cyborg -    sex alteration surgery -    disability

TRANSHUMANISTS UNDER NO ILLUSION

‘Natural is meaningless’ (miah) -    not meaningless, but you might disagree with it

Prometheus (2 versions) – THIS MYTH IS NOT HELPFUL. WHY PICK THIS MYTH? -    overpower god -    cunning of human to be as good as god

ME A WIDE RANGING THESIS – TOO AMBITIOUS DISAGREE WITH THEORY OF SCIENCE/MEDICINE/TECHNOLOGY – PHILOSOPHY OF BIOLOGY CERTAINLY REFLECTS HOBERMAN’S EXPRESSION OF PAST DISAGRE WITH REPRESENTATION OF TRANSHUMANISM DISAGREE W DIPICTION OF GENETICS

IVF – SAME KINDS OF ARGUMENT – NOW WE HAVE, JUST THIS WEEK, LAW LORDS PERMITTED ‘SAVIOUR SIBLINGS’

VIRTUOUS ROBOT?

FRIDAY AM

Anna

Corporeality

Heidegger

Man is man as far as is hand can reach, as far as the purpose of his world extend

Become corporeal by means of hand and speech

Why the hand and not the leg?

Corporeality process

Man assumes emotional figures – existence

Postmodern

We don’t understand ourselves

Universal values have vanished

Gypsies of Europe

Predicated by Nietzsche

Great strength is greatest priority

Speech is essential part of our corporeality Doesn’t pertain only to doctors or semiology, or grammarians, literates, etc

Speech is only an extn of the hand

When hand no longer writes through hand, but through speech, what will happen -    breaking of art, where hand forms meaningful words

what will happen with speech and words -    changed only into symbols

speech taken over by semiology

profound meanings of words will dwindle

transformed into a machine, tool?

Production merely

Physical education responsibility for speech

Hand and words are only means to transcendence

What will happen with the hand?

Managed by computers

Transcendence by sport is victory over self

What about a typing competition -    give someone a title and ask them to write it

LEON CULBERTSON

Hoberman – dehumanisation- ME:  but  he meant alienation (and he is right)

ME: do we need a precise notion of human? (I think he is also arguing for this)

Warnock – embryo rights – she - we don’t need to get into humanness (ME: but that agrees w Warnock!)

humans – as homo sapiens (strong) -    dignity persons (weak)

we are all human – product of our actions

ME: prob is that we do operationalise human!

Dehuman, not less than human Use to work human in weak sense, but not humanness

Edgar – dignity – undignified – don’t talk about dignity when feel undignified

Human definition arises out of sense of being dehumanised

Persons need not be human (McNamee? ME: no!)

What gives sport value?which sport, for whom, etc?

Contextual

Clear view of t misunderstanding Terms such as dehuman used in specific kinds of context

Contrasts – different beings -    prob is that they are oft drawn in way -    drawing t line – ME: we don’t like it, but this is how people conceptualise issues!

Degrading – lack of feeling is inhuman, but not non-human

GEOFF PARSONS

Selection as a vehicle – throughout sport and elsewhere

Conflict of differing philosophy in sport

Different between objectively measured sports and subjectively measured (team sports)

Gov policy driven by sports councils – uk sport

New athlete contract just published -    given to 16yr old, 17p document -    says: we all agree that the overriding thing is to win medals at Olympic championships

institutions of sport act as guardians

performance directors in governing bodies – their job is to win medals – they now have subjective method by which to select people – Olympic profiling – to receive funding and stay in programme, reqs to meet perf directors assessment of what is Olympic profiling -    is asked ‘if athlete wins championship for 3 years, would they get on programme’ – performance  dir says no. -    creates biased selection policies

In objective sport, should be no selectors – performance  on day matters only

Blame governing bodies – complicit, rejected commerce, thirst for resources,

Government role -    top down agenda in very item -    UK Sport cd: seeking perfection

Performance director should be tied to the performance of the athletes for which they make selection

When threatened, sports institutions act like nation states

British sport should celebrate process, rather than medals

WHAT ARE GOVERNING BODIES FOR YOU? WOULD YOU REPLACE THEM WITH SOMETHING ELSE? DIFFERENT PEOPLE?

BIOETHICS AND DOPING

Definition of sport – psychophysio sphare

Doping in sport relationship – if doping is alteration in different relational spheres -    intra personal – relationship betweenathlete and body o    doping – loss of develo of personality o    limit – surpass oneself -    inter personl – negation of propium over sport -    doping compression of games diemsion o    not charac by gratuitousness o    perversion

doping = rejectiung principle outlayed breq to entre into comp

Dr Giovanni Franchi Universita di Teramo giovfranchi@libero.it

ALUN HARDMAN

Different kinds of injury -    injury prior to contest -    iinjury sustained to non-contXX -    injurie sustained as reslt of actions from non-contestant -    injuries sustained as result of foul play

referee must top t game – ME: t player should adopt some referee status -    t rule is badly formulated -    self-offciating/governing -    is it fair only if we interpret t incorrect reading of the rule?

Fraleigh Right Actions -are players following guiding of principleof equal of opp intentionality is imp non-moral principle

health/well being not only concern -    do not stop player if ‘normal injury

ME: if injured player is on attacking team?

Principle of voluntary and dual assessment

Permit medical team to attend to athlete without ceasing play

Is guilt approp response to injury? McNamee, EJSS 2002 -    shame and moral failing, guilt and shame – guilt proper respons to transgress of code, shame is not reaching an ideal -    -if harm unintntionly, rawls says subjective guilt – guilt sign of virtue – causally responsible but not morally

GRAHAM MCFEE

Popper – overstaed claimn of sci method rejected

Account of science -    Popper? -    Creation science -    If meet Popper

Kuhn – different between natural nad social science -    truth denied, t pomo -    natural sci – 2 phases: normal sci – unpacking of past insight, paradigm in place – crisis and revolution when absence of single paradigm – makes no sense -    physics etc failure to invoke conXX over fundamentals -    sociology always contested  - Kuhnan explans why

limitations – socio,psych have competing view of social world Kuhn – how align?

But should be – social world – perspective dependent

question about why in social science you have paradigm claim as barrier to conversations between subject areas?

State of Play Conference (2005, April, Preston)

‘State of Play’ Conference UCLAN 27-28th April 2005 Day 1: Programme for Wednesday 27th April (revised)

Arrive UCLAN Foster Car Park/Reception

Registration and Buffet Lunch 10am -12.40 Foster Building Scholars Restaurant and Bar

Opening Plenary 12.55 - 1.25 Ian Blackshaw The Court of Arbitration for Sport Comes of Age Adelphi TVI Lecture Theatre

Panel 1: Doping 1.30 – 3.30pm Richard Cramer Hazel Hartley John O’Leary Andy Miah Adelphi TVI Lecture Theatre Chair: Hilary Findlay

Panel 2: Civil/Criminal Liability 1.30 -3.30pm Dave McArdle Mark James Viv Ivins Adam Pendlebury Adelphi LT 114 Chair: Simon Boyes

Coffee: 3.30 - 3.45pm

Panel 3: Image and Spectacle 3.45 - 4.45pm Susan Fletcher Sefletcher2@uclan.ac.uk Paul Boylan Adelphi TVI Lecture Theatre Chair: YvonneWilliams

Panel 4: Post -Fandom 3.45 – 4.45 pm Simon Gardiner Robin Manser Jonnny Magee Adelphi LT 114 Chair: Paul Wilson

Close of Day 1: Deepdale Wine Reception 6.30pm –Dinner 7.30pm

Day 2: Programme for Thursday 28th  April (revised)

Panel 5: E.U Freedoms 9am – 10-15am Geoff Pearson Clifford Stott Simon Boyes

Adelphi Conference Room Chair: Steve Cornelius

Coffee: 10-15am -10-30am

Panel 6: Discrimination 10-30am -11-55am John Wolohan Yvonne Williams Steve Cornelius Adelphi Conference Room Chair: Mark James

Closing Plenary 12- 1pm

Hilary Findlay

Adelphi TVI Lecture Theatre

Weds

Image and spectacle

Sports celebrities

Golfer Doug mccormack

Justification for right of privacy in US

Tort of passing off in uk (since 2002, before ‘deformation’ only course of action, and relies on negative), protects (no right of privacy in uk)

2 types of practice - product endorsement (celeb assoc w product) character merchandising (product is about celeb buut not clear whether endorsed, not protected by copyright – de minimus principle – too trivial to be protected) need to register celeb name as trademark as early as possible

trademarks -    photos and other portraits (is possible to register as a trademark) – image that I registered is trademarked, not all images of that face – must be capable of distinction

photos of people at work – eg cantona scoring goal – diffi to estab, since other traders might want to use them

justice lavey – elvis presley case – where there is trade….that person has no right to stop others..legit trading in image

must use images that are distinctive

with endorsements -    goal of advertiser is to use recognition factor to draw on ‘halo’ effect – eg. Because beckham is brilliant footballer, if used for Gillette, tht must be brilliant too

talksport commissioned agency to produce 3 box sets – shorts w skidmarks eddie Irvine on front – without permission – no issue w photo, since itw as purchased from agency, photo had also been changed – mobile phone transformed to radio – justice lalley decided it was passing off – ref mccullock v may (where same line of business imp) – ‘common for famous people to exploit their images….reason why large sums are paid for…those in .believe that..endorsee takes benefit – upheld by Court of Appeal, despite criticisms on judgement

need to clarify whether good will

need to show actual damage

diffi to bring action on passing off

in this case, it increased pay off from £2000 to £20000 because Irvine said that was minimum he would accept for this kind of endorsement – often, ends up this way, so can take the risk

David Bedford – 2 lookalike figures- directory inquiries service 818 – he had not endorsed. But if he had tried this on passing off, would have had problems – that image is no longer viable, and it wasn’t actually his image that was good, it was look-alikes

If you had personality rights, it would have a remedy

Justice Lalley in Talksport and Irvine talked about modern commerce, but Art 8 of ECHR might have worked – celeb endorsements: any negative publicity, might be transferred back to product, thereby reducing brand equity, so imp that reputation be maintained.

HRA came into force -    Art 8 and 10, -    Does not fully incorporate ECHR (incl privacy right) -    Though courts have interpreted them in context of eCHR8 and 10

Court considered both 8 and 10 in separation, since neither had priority -    court of appeal found in favour of defendant, The Mirror

A & B and C – footballer – newspaper published details about his relationship Lord Wolf ‘ where an indiv is a public figure, he is entitled to privacy in appropriate circums..though must accept that will be subject to scrutiny by media’

Justice Langley, no interim injunc to publish rev of beckham’s former nanny -    story in clear public interest -    nanny ‘fortune based on them having successful marriage’

are we all entitled to t same degree of privacy? -    athletes, politicians?, is it relevant that sports stars often treated as role models?

Other issues Deformation Data protection

Beckham in junction – analogy w Naomi Campbell case – mirror found out she had taken drugs, when she claimed she had not

V fact that beckhams are unique is because of this marriage, so perhaps it is in public interest

Q&A

Athletes as role models? Evidence? -

negotiator

licensing of computer programming

language concerned – English or Japanese – French as comprormise

spectacle of the sport

the spectacle has become international big money

so much money involved in org sport

challenged by Internet

essence of spectacle is money (as control of spectacle)

control by contract (player contracts in particular)

3 parties to every player contract - player, organisation, trade union

baseball, prob not steroid use, but that contracts arranged by trade unions prohibit testing -    eg of how powerful union can be: unfair labour practice claim -    john mcgee – player contracts out of control – to detriment of players themselves

in each contract, because dealing w people, not product like any other – need meaningful relationship

research opponents

confidentiality agreement essential -    between player and association -    do not want others to know what you are paying -    nobody knows what other players are getting -    to avoid constant battles

other aspects to spectacle -    beckham nanny: she breached confidentiality agreement, failure of lawyer o    lawyer did not write contract to convince nanny that disclosing would be risky o    why did she go to paper? They promised her indenification – paper knew she would breach agreement and they agreed to pay it o    could have used liquidated damages conract – give incentive to her not to go to paper o    lawyers should have realised that someone would come forward

fantasy sports -    who owns statistics? British law says no. US authority say the people who manufacturerd it have a right to exploit it -    in US fantasy football worth $3billion dollars in profit -    it wil not end up before court, because too much to lose for both, so negotiation inevitable -    in UK, says this is public info stats

Q&A

Motorola downloading info, creating more info out of raw data – breach of copyright issue failed -    unjust enrichment for US, not similar to Motorola

for fantasy football – is it fair for someone to profit from something they did not produce -    implied license, so will compromise

Thursday

EU Freedoms

Simon Boyes, SL at NTU Law School Caught behind or following on?

Cricket

Kulpak

English cricket system now moved to permitting 2 overseas players in county teams

Implications -    oppo to play against intnational players, but result is fewer opps for local players to get into team -    lottery funding goes to overseas players

bosman case 2key elements -    transfer fee at end of contract, now in breach of Euro articles treaty (restrtc freedom) -    abolished discrim on basis of nationality on limitations to foreign (EU) players

for cricket, transfer fee not relevant really

player quotas has had a relevance

kolpak, analogous to second part of bosman – right not to be discrim against, once in employment – he was a Slovak handball player and was goalkeeper in second division – was subject to quota inquiry

euro court of justice – if association agreement, gives right not to be discrim against based on nationality –

cottonow agreement – similar to kolpak - kolpack does not give right of access to employment, but merely, once in employment ,not to be discrim against

recent change I work place employment

used to be case that commonwealth citizen could obtain working holiday permit – now changed – acting as sports person is not ok – implic for west Indian states and south Africa – but if can satisfy criteria and state no interest to play test cricket, is relatively easy to get in –

EC sees as imp – new strategy, continue w rules but use incentive scheme – give counties £200 per player per day for evry English player  = £20,000 per year perhaps – trying to drive foreign players out

Not appropriate, since tends towards discrim

Has the effect of discouraging teams to not employ foreign players

Cricket is different and this is making a wrong choice

Symptomatic of sports

Assumes can transplant bosman to other sports

Cricket can argue for some level of discrim

Uk only member state that offers opp to play pro cricket

For bosman, argued would diminish opp for pro players, but dismissed because of reciprocal opps

For cricket, this reciprocation not possible

Structure of cricket different from football, impc of test game cannot be overstated – test deal with ECB and sky – stated they needed to do this because test game provides money for grassroots –

Health of England team signif to sport, so more worthy of protection

English high court since 1978 kerry pakka case – test cricket a value worth protecting

Describe as a structural rule

Geoff Pearson, Liverpool Uni, Management School Football related Legal responses to football holiganism, policing of football grounds

Keeping a sense of proportion: Football banning orders and the fundamental freedoms of ‘known’ hooligans

Problem -    English fans reputation for disorder -    40,000 english fans in 1998 -    60,000 man u fans in 1999 -    euro 2004, upto 250,000 attended

serious disorder at france 1998 965 arrests at Euro2000

probs w previous Banning order legislation

Football Disorder Acts -    banning order for hooligans, known to cause trouble -    not new, first introduced in1986, Public Order Act, sect 30 -    Football Spectator’s Act o    If convicted of crim offence relationship to football, prevented from travel when game takes placeabroard

1999 legislation unsuccessful

Football (Disorder) Act 2000 -    Schedule, Sction 14B, new type of banning order to be more effective o    Banning order on complaint (as opposed to conviction) o    If suspected hooligan – big leap! -    If suspected to have contributed to violence, and if court satisfied, magistrate must impose order -    Police watching suspected hooligans, compiling evidence, and proceeding on civil procedure -    ME: how long?

Civil Libertarian concerns w baning orders on complaint -    treaty of EU – right to leave one’s territory -    ECHR – Art 4 liberty and Art 6 fair trial (because introducting punative criminal penality on civil stat case)

Gough a Smith v Chief Constable of Derbyshire (202) QB 1213 -    ECHR (was banning order contravion on Art 6? -    EU treaty (was it proportional) (Does it apply in this case?)

was it applied in gough and smith, and are banning orders on complaint a proprtioanl response?

Proportionality Principle -    must be suff imp to justify limiting a fundamental right o    how serious a prob is football hoolianism? Court don’t like it, though not sure it is really so signif •    every week English fans travel abroad, so number of incidences is quite small •    media hype-up, we don’t see much of uk violence o    Statistics of arrest, conviction, death and injury •    Suggest prob is reducing, no stats on death or injury (1 per year for 25million spectators) •    For Euro2000 arrests, only one was charged w an offence o    Comparison w other cross-border crime (paedophiles, etc) -    measures must be rationally connected o    how imp are banning orders on complaint to t control of football crowds? o    Are those involved in disorder known hooligans? o    Does preventing known hooligans travelling to matches necessarily prevent crowd disorder o    Not actually known hooligans gathering together that causes probl; if properly policed, no probs; but where not policed well, problems arise -    no more than is necessary o    are there other ways to control problem rather than infringing these rights? •    Banning orders on conviction (ME: but can they get convictions? Otherwise, why so few cases?) •    Policing tactics •    More efforts on Fan Policing (support legit expectation of fans) (typically, where a few incidents of violence, police go straight in to entire crowd, rather than select few) • -    De Freitas v Perm Sec of ministry of Agriculture (1999) 1 AC 69 o    This test not thoroughly applied in Gough o    Infringements of civil libs are out of proportion

On strictest version, talks about least restrictive alterantive -    not just whether connected or necessary, but whether is less restrict alternative

ME: what is basis for concluding that courts are so influenced (out of proprtion) by hooligans on tv?

Clifford Stott, Uni of Liverpool

Proportionality in psych of riot

Science of crowd dynamics

Football crowds not just hooligans

Crowd dynamics and riots at international tournaments -    those arrested and convicted are not known hooligans -    identity based processes involving intergroup interrels -    police play pivotal role in structuring these rels

category of being an English fan affects way they are policed -    creating enviro empowers those seeking to create disorder -    they are facilitated by the form of policing -    level forceful and indiscrim forms of policing, based on reputation, rather than behaviour -    English fans arrive and begin to perceive form of policing as illegitimate – see this as affront to rights

When fans perceive policing as legit, then changes dynamics -    eg Scotland fans, emerging sense of leigitmacy in police and self-policing

absense of disorder has little to do with fans, more to do w rels

implics for policing

Euro 2004

collab w PSP (one of portugal’s two forces) create enviro consistant w research

risk is dynamic risk emerges, not fixed interaction of groups influences level of risk

‘balance’ in risk scenario -    police in balance implies low profile deployments, results in spych and behav different

ME: is it difficult for police to target arrest in big crowds?

Discrimination

? South Africa

Chances of aids transmission in sports arena v slim so not subject to compulsory testing, since is unnecessary and in legal context of south Africa, is v precise about rights to eg human dignity, privacy, equality, choice of profession

Chalk v California -    Judge: plaintiff will have to estab that defendent sporting body is receiving funding from gov and that enjoys public patronage

Aids now (since last week) considered a form of disability, which changes sitn somewhat.  Justice jones: confidentiality vital to public and private health

Recog right to dignity, intrinsic value of human – respect and concern

Diffi to force athlete to undergo a test

X v Y and Another

Cf hiv testing and doping? -    hiv more invasive and less accurate

Steve Cornelius, Uni of Johannesburg, Centre for Sport Law

South African Measures to Combat Unfair Discrimination in Sport

Assumed that in SA apartheid implied merely racial, but also concern about gender and disability

Bill of Rights (starting point for all law in SA) -    s 8.2 – binds everybody -    matter of public law

right to non-discrim -    s 9.4 -    no person may unfairly discrim -    not all discrim is bad o    s9.4 prohibits unfair discrim (implies that there is fair discrim) -    s 36.1 – limitations clause (law of gen applic; based on human dignity, equality and freedom, in democratic soc) -    s9.2 – affirimative action measures

legislation -    prom of equality and prevention of unfair discrim act o    if unfairly refuse to consider applic, then unfair •    provides for action, do not need to show actual harm o    denying access to club o    failure to promote diversity in selection of rep teams

SA Sports Comm Act -    coordinate provision and upgrade of facilities in disadvantaged areas -    assist in development (lot of emphasis on women in sport)

Yvonne Williams

Do volunteer coaches have right to refuse responsib to coach people w disabilities?

DDA1999, part 3 – sports coaching is a service, so cannot discrim against a disabled person by refusing to coach or way they do it.

Direct discrim  - treat less favourably then how treats/would treat others

Indirect discrim – same activ offered to all, but disabled treated less favourably or put at disadv

Case in US, using computer aids to hunt

John Wolohan

Discrim laws in us

Racketball player w disability, wants to play w able bodied, and instead of one bounce in the game, he wants to have two – adjust t rules to accommodate a disability

Child w disability takes longer through highschool – rule that only under 19 can play in school sports – so cannot play – but rule is discrim disability?

Casey martin – pro golfer, trying to qual for PGA tour, to get card need to go to qualifying school – he has made it to stage 5 until which he has been allowed to ride a cart – requested for final stages and pga tour – pga tour reject request –

Supreme court grant right to use cart

Walking in golf not really fatiguing and deven if it is casy martin’s fatigue getting in and out of cart is greater than well-athlete

Decided that essence of golf was shot making

Does pga have right to set rules? If pga says it is essential, who is the court to say otherwise?

Asking to modify game just so you can play is not reasonable – it is creating a new game -    able bodied player will have to learn how to play you in different ways, this is not fair

is it a ‘reasonable accommodation’?

Closing Plenary

Hilary Findlay

Canadian Independent Dispute Resolution Programme

Genevieve Turninkey? -    ‘dispute resolution’ ‘real growing activity’

ian blackshaw author of book on ‘mediation in sport’

rules of an arbitration process as instrument of sport policy

what is approp scope of review for sport dispute? -    how broad are grounds of review? -    What is standard of review? -    What scope of authority, when error found?

Appeal layer

If appeal panel has made error, then judicial review (v narrow)

April 2004, dispute res intro to canadian sport

Doping infraction for horse, trainer acknowl that horse given substance by vet that was prohib – this was not raised in hearing, since accepted by all – rules state where horse doped, trainer responsib – but held that vet responsib – strict liability, so trainer liable – parties waived internal appeal process – q about scope of arbitration – hearing de novo (everything relevant should be seen – argued this was too broad –

Second athlete not selected – went directly to arbitration – include first and second round or only second, where issue

Broader scope of review, further usurps authority of sport org

What standard of review to determine whether error?

Technology and Sport (2004, San Sebastian)

San SebastianDec, 2004

Basque

Thank you very much -  Milaesker Hello – Kaixo

Regards - gorantziak

Zer moduz – how are you

Aldor Cobanera

Edurne Pasaban – Alpinista (athlete?) elite,  Mountain Climber -    only woman on opening panel -    since 1998, major changes in technology -    in climbing, far better known thanks to technology -    materials, but also other technology connected with communication -    ICT to stay in touch through mobile phone technology -    Telephoning from summit -    Breakthrough in medicine and technology o    Can contact physicians  when injured in mountain -    Even more important in a minority sport -    Now when on expedition, now take laptop, mobile phone, web access -    It is still difficult to peak -    Technology does not help that much

Victor M. Izquierdo Loyola, Subdirecter General of the Info Soc Enterprises, Ministry of Industry, Tourism and Trade -    ministry of trade -    EC paper on IT o    Talks about how applics and experience should be present from beginning of research design o    Users must be the consideration of a product development

Noberto Santiago Elustondo, President of GAIA -

Jaime Lissavetzky Diez,  Sec of State for Sports and President of the Higher Council for Sport -    subjects have economic and social impact -    physical activity,  and doping -    which is most important? – boosting of physical activity, particularly interesting. -    Enormous amount of consumption

Juaqin Villa, Dept of Innovation and t Knowledge Society -    need to create social network for innovation -    innovation broader than technical and corporate o    also management, services, o    not just in company enviro o    society in general o    innovation as a social phenomenon o

ME: Nobody yet has actually addressed the social concerns, but they have been intimated.

Kim Blair Technology and Sports: Developing Consumer Products

2000 Olympics -    Speedo Fastskin – received tremendous pulblicity, Speedo said, anyone can have one, so was ok. -    Sydney pool was state of the art – hardly discussed -    Reason why records broken in Sydney, was because of the pool o    Though did not have the political resonance

Trek Madone 5.9 Bicycle – I used by Lance Armstrong in Tour de France

Technology and Golf -    1920s Steel Shafts replace hickory shafts -    1960s: fiber glass, aluminium titanium shafts – never made it to market

change was an ‘accident’ -    material not caused change, but that titanium springs -    St Andrews changed spirit of rules – face of club has spring like effect -    In golf industry, believe that curve will flatten out -    When technology introduced, see sudden change, then flattens out and comes back to athleticism

Sports Producct Industry

Attitude to risk -    nuclear, civil engineering and aerospace industry o    slow to adopt new technologies o    whether or not technology is viable o    high regulatory climate -    sporting goods manufacturer - o    Marketing and fashion driven •    Marketing often head of product development •    Signif vol of product sold by brandingt •    Signature products, star endorsement •    Need to seel your vision and the ‘wow’ factor o    Time to market is fast •    Typical small changes on seasonale schedule •    Continuous product intro o    Research horizon •    5 yrs is long •    less than two years typical o    Personnel •    Closed network o    Highly secretive •    Technology barriers are low •    Extremely high lev of secrecy on new products •    Control ofIP is reqd by sports company

No innovation infrastructure in US -    nothing llike SPORTIS

Before 2004 Tour de France, Lance Armstrong called sponsors wanting to put together F1 team – Trek Nike Oakley, Giro and HED – to form collab effort between them

USOC -    relies on product sponsors for nearly all product R&D

Developing Sport Products: Product Attributes -    need to understand all -    aesthetic -    attributes of association -    perceived attributes -    emotional attributes -    style

User-Centred Focus -    talk with lead users – passionate sports people o    understand what they like in their product o    understand why they are passionate about sport o    understand how sport influences daily lives o    understand how daily lives influ their sport -    understand core market o    development surveys o    validate t data o    typically use demographic data -    understand own business o    innovation/product needs to send right message about company’s vision

Cost Sensitivity -    eg. Consider cost of raw materials o    golf tee about 2x cost of materials •    change in material has huge impact on cost o    Golf club about 20x cost of materials •    Change in material has small impact on final cost •    Can change to more expensive…

Heart Rate monitors – 20yrs ago, people did not understand it. Now a company come out with a product and lot of effort in training consumers in using that tool. Plan for and expect slow product adoption

Never underestimate challenge of changing consumer behaviour

Capturing Product Value

Limiting comp -    retain control of IP -    retain key assets o    people, trade secrets, licensing, partnership agreements -    typically, technical barriers are low – easy to copy something new

Developing Alliances - Large multi-nationals -    have patents in place -    development clear vision for product from customer’s viewpoint -    more complete t concept t better

Universitie -    useful for product testing -    can be useful for prototype development -    due diligence required on IP ownership

Venture backed efforts -    develop venture division of your company -    solicity ideas from inventors (internal or external)

consultants -    highly recommended to have ‘insiders’ on team -    provide industry expertise -    prodide industry introductions

Rene Eijlens Innovation for Gold

Beat the heat Clothjing -    hat used to remove heat from head.

European Paralympic Committee -    from therapeutic to elite -    technology central to this development

LUNCH

Xtema… - golfer

FRIDAY MORNING

Xabeir Azkargorta -    medico y entrenador de futbol

En busa del futbolista excelente Luis Fradua Universidad de Granada

Nestor Lucas Cairos System: the intelligent football

Radio based tracking system that analyses data of ball and players in real time

Useful for referee, for graphical presentation of replay

Xabier Azkargorta -    technology is leading to an easier contest and reluctance to train as hard -

ICSSPE Pre-Olympic Congress (2004, Thessaloniki)

ICSSPE Pre-Olympic Congress,Thessaloniki, August, 2004-08-07

Bengt Saltin Energetic limits to performance

Leo Hsu

Concept of the good foul Bsketball Soccer

Good foul unethical -delib interfere - no equal opp for contest -    not agreed on

good foul not cheating -    cheating: intention to deceive and unfair adv -    good foul: intention to break rules  plus unfair adv

simon ‘strategic foul’ -    intention and action -    penalty might become adv cheating\break rules deilib avoid penalty inend to deceive win or gain adv

good foul breaking written rules delib expect to accept penality win and gain adv

a good player… -good intention act rightly keep spirit

concl good foul -    not cheating -    against purpose of sport -    morally wrong act -    indicates deficiency of rules -    violates spirit

Q&A Scott: opponent stalling – good player wants to play good game, so breaks a rule in order to create a good game. Is this good foul? -    response: NO

Sigmund: Good foul morally wrong act, but ethos

Leo: depends on defn of morally right: - if ethos is morally justified, then ok, but if not, then is morally wrong.

Heather

Beauty of Olympic sport typically allow more than one way of playing the game Not clear whether poss to decide between beautiful and corrupt -    elitism, sexism, racism

need to estab criteria for changing sports practices

set out Rawls’ method reflective  equilibrium

narrow -    justif ororig posn, if match -    choose strongest convictions as fixed points then work backwards

wide -    demonstrate why justified to apply in  specific contexts, by increasing breath of test

benefits -    clarification, systematic, democratic

going through process of wide refl equilib help clarify views

can uncover more systematic

democratic: in context of other beliefs. Where conflicts with other values, then indication of problem

disadv with this method -    uniersal and cross Cultural undemocratic -    indivs and their interests

diving or shirt pulling in elite soccer, decision could include everyone in debate as to whether is acceptable – these people unlikely to be aware of internal goods of game -    they’re likely to have limited knowl of game (HMMM) -    to follow wide refl  equilib

abstraction is undemocratic, since must disconnect from cultural context

democracy not about truth

while wide refl equilib is useful – it is too thin, since too far removed from sports practices to have any normative force -    could not determine which ethos is most justified.

Tradition practice bound reasoning: -    Which criteria? -    Who ought to evaluate?

Liberal interpret of practice community allows spectators, etc -    only views about goods internal to game count -    a limited  democracy, providing correct credentials

Gunnar: -    would work in new sports, with fast developing ethos -    would rely on imagination of people to a much higher degree

Mike -    liberalism v communitarianism

Sigmund Loland Fairness in spor t- critical comments on Olympic competitions

Not Fairness as indiv obligation, but ‘structural’ fairness -    when is a competition fair,not when is a competitor fair

fairness in sport -    competitions -    relevant and non-relevant inequalities -    fairness ideal -    implementation of fairness in practice

gen principles of fairness -    eliminate or compensate for inequals that exert SIGNIF influ on performance o    indivds cannot control and influt o    for which cannot be held responsible

-    conseqs for Olympic  sport?

Inequalities -    ext conditions -    person-dependent inequalities: INCLUDING GENETIC MAKEUP, BODY SIZE, ETC -    system inequalities

ext cond -    direct competition – standardisation -    indirect comp (outdoor) – seeded groups, drawing of positions

person depdendent -    sex and age, over-clasficiation (sex classification seems reasonable in some sports – where biological differences are significan, though in others, they are not justified) o    – ME: interesting analogy for genetics, would we seek to ensure athletes are all the same age? To what degree? Where it seems to have some influence on performance, we should. -    body weight – under classification

CAN SPORT SUPPORT ADDITIONAL CLASSES AND DISTINCTIONS AND DO YOU THINK IT POSSIBLE TO LOOK TOWARDS PARALYMPIC DISTINCTIONS TO IMAGINE HOW IT MIGHT FUNCTION? - A QUESTION ABOUT THE SPORTING SPECTACLE AND ITS VALUES

TALENT IDENTIFICATION IN SPORT

What makes a Champion?

Talent -    natural endowment or superior ability -    single most imp factor contributing to achievement -    other factors include

identified developed selected science or art?

Intuition, rolling dice, magic, sport science (multidisciplinary, evidence based)

Nature v nurture

Genetic endowment -    intrinsic potential 46xy -    structure, function, behav -    genetic manipulation -    next doping frontier?

Environmental influence -    extrinsicfactors

Suzuki Method -    all  Japanese children speak Japanese -    inborn greatness or mediocrity not known -    advanced ability can be nurtured  in any child

Why does it matter? -    parental imperative -    Olympic imperative -    Financial imperative

Jason Gulbin -    South Australian Sports Institute -    AIS -    National Coordinator of Talent Search -    Published on athlete profiling, ex induced muscle damage

Thomas Reily -    Liv John Moores -    President-elect of Int. Soc Adv. Kinanthropometry

Darlene Kluka -    Grambling State University -      Volleyball talent

Jason Gulbin Paradigm Shifts in Talent Identification National Talen Search Coordinator, AIS

Concerned about young athlete and talent identification – but much of the work is also on older athlete

Terminology Talent (identification/detection) – athletes from outside of the sport (non-specialist, quasi scientific approach, to examine predisposition for a specific sport) Talent Selection (within the sport, watching athletes) Talent Development (vital to process)

Intentiaonal Search for answers Ireland (NCTC) 2001 -    factors prpmoting and inhibiint  success of H Performance players and athletes n=207

USOC 2002 Talent id and devel of US Olympians

AIS 2003 How do elite Athlete develop n=681

NZAS 2004 Linking promise to t podium taskforce report

Why such a focus on this area?

Australian Typical spending patterns ($AUS)

Costs $37m for a gold medal

$8m for any medal

(Hogan and Norton, 2000)

reducing costs isa  huige bonus

US Census Bureau 2000

Population for Oz significantly less than other countries, so identification critical

National Talent Search Program 10 yr programme www.ais.org.au/talent in each academy, talent search coordinator phase 1: ask pe teachers in highschools to collect data for basic phys test phase 2: submitted to talent search coordinator phase 3: if athlete good, invited to talent devel programme

program  issues -    growth and devel conundrum (too much to measure, children of same age too different) -    labour intensive  (reject around 95% of data from schools) -    athlete acceptance uncertainty (not all kids want to do selected sport) -    variable enthusiasm of schools/teachers -    information privacy concerns (now, they use id numbers, rather than names) -    inability to respond to immediate needs of coaches in age group ( -    emerging adulthood and retention

paradigm shifts -    broad – focussed -    young – older -    novice – experienced -    schools - public domain -    TID

e.g Cycling -    ad in paper for talented female cyclists for 500m event -    females 18-26 -    non-cyclists -    explosive leg power -    competition history -    recruitment via the media -    initial screening n=247 applicants -    peak power, 30 sec av power, vertical jump test -    selected 26 girls -    age 16-29 (played various sports: bball, rock climbing, athletics, rowing, netball) -    lab performance: peak power: (1300w, av power: 700w; 10+yrs),  these athletes peak power: 1134W, av power: 625W – after 6weeks (gardner et al, 2002) -    performance in less than two years, 5 athletes when on to win national comps

Paradigm shifts -    simple – complex models -    from physical to physiological -    focused cohort of 32 selected, based on: o    water ‘feel’ o    school grades o    parental background (molecular biological approach will be critical in advancements)

paradigm shift -    centralised – decentralised -    generalist – specialist

Regional postgrads -    offer maters by research (cycling) – fee-free position plus stipend, to assist talent search coordinators and also develops local support

Summary Consider maximising talent harvest by supplementing traditional TID approaches

KIM SCHIMMEL Deep Play – political hierarchies  in  new Olympics

Reconstitution of Olympic space -    nato resources -    70000 troops -    greek forces -    us coast guard -    us special forces

private security entitites and gov alliances

eyes and ears of the games

cancellation insurance -    first time in Olympic history -    $170m coverage/$6.8m premium  usd -    terrorism, earthquake, landslides (not construction delay)

Olympic Spirit -    if terrorism threat to Olympics real, then why stage it in  modern world (july 26, 2004, b KI Angelopoulous)

www.anti2004.net

current cost of Athens 2004  6billion euros, 1% of Greece gross product

Beijing 2008

Kristine Toohey -    (Sporting) Legacy of Sydney (Cashman) -    economic (direct and indirect) -    vbuilt environment (nonsport) -    info and education -    public life, politics and culture -    sport o    elite, mass (FOCUS ON MASS SPORT IN THIS PRESENTATION), financial, built infrastructure -    symbols memory history

Mass particpation as Olympic legacy (grassroots sport) – theory/intent -    de Coubertin -    Olympic Charter -    IOC invlve with sport for all, since 1983 (samaracnch) -    IOC Sport for aLL commission -    IOC WHO 5th World SFA congress 1994 -    SFA congress declarations sponsored by IOC, Seoul, 1996, bcn 1998, quebec 2000 -    IOC Legacy symposium 2002 (Hein Vergruggen) – to remain educational -    55 papers: mass participation addressed in 3 (2 winter sports)

Ressearch Q -    given intent, does hosting OG boost mass sport particpation in host communities?

Past Olympics -    international conf held in late 1980s in seoul, korea -    reps from 5 previous Olympics -    agreed that mass participation most imp -    but little evidence that actually happens -    2 exceptions o    LA 1984: AAFLA – runs number of programmes o    BCN (Truno, 1995) o    Sport paritipation in BCN •    1+ per week •    1983 36%

Sydney 2000 -    in aus $60m dollars per gold medal

Houlihan from ASC

Centre for East African Running (2004, Glasgow)

Glasgow University Symposium Possible Causes of Success of East African Distance Runners March 8, 2004.

Keith Johnson – genetics dept

‘Off the track, in the field’ Yannis Pitsiladis

Dr. Bezabeh Wolde, Sec Gen Ethiopian Olympic Committee

Sampled entire Olympic team Team trains together

Kotebe College of Teacher Education, Addis Most of athletes from Shewa and Arsi (central part of Ethiopia) -    altitude 3000m (Addis Ababa is 2400m) Bekohi, Aris Province -    deratu tulu -    kenenisa bekele children’s journeies to school by foot/running/cycling World Champs Paris, 10000m -    gold, silver, bronze all Ethiopian

Kenyan First Olympic Gold – Neftali Temu, Mexico Olymmpics Mike Boit, bronze medal 800m 1972 Munich, Olympics Commonwealth Gold, Edmonton, 1978 Nambi? Nandi? province Rift Valley St. Patrick’s High school – boys school -    many Olympians from here tea break – important? Itigo Girls High School Pupils running to school Morning, for lunch, and afternoon (parents must find food for them) Kaptagat Training Camp – Patrick Sang -    Global sport sponsorship -    Joseph Chelimo, Head Coach -    Eliud Kipchoge – gold 5000m World Champs, Paris 2003 -    Richard Limo – Gold 5000m, Edmonton 2001 -    Camp has no electricity -    Cooking fone in pots

IOC Consensus Statement on Sport Nutrition 2003 All cooking done on fires, very precisely

Daily diet -    average carbo 606g -    body weight on average 58.6 -    near perfect ratio

Fluid intake

Eliha Lagat (boston marathon)

IOC Camp – Kipchoge Keino (most well known of Kenyan athletes)

Chirchir training camp -    sampled athletes -    tea important again -    ran in morning without breakfast, and return to have tea with 3 slices of bread

Chepkoilel Stadium Kaptagat Camp (FILA) -    moses tanui -    unpasteurised milk for tea

Amos Biwott (3000m gld, Mexico 1968)

Fatwell Kimaiyo Gold 110m 1976, hurdles

Commonwealth games perth 1962, seraphina antao, gold

“whether there is money in it or not, running is in the children’s blood” school teacher

Acknowls John robertson bequest, uni of glasgow EOC, EAF, Wellcome Royal Soc Carnegie Scotland Event sponsored by Glasgow City Council, Abgene, WWR International, Cranlea

Used Bleep test – had not heard of this test before. -    results under analysis -    1000 kids tested in Nairobi

no obese kids in nandi, but plenty in nairobi

agali (staple part of diet) -    similar structure to rice

John Bale

Pre-colonial period Cultures of running Myth of natural athlete

FAM Webster arranged comp between spear throwing and javelin

Modern period When running became racing Refute idea that these Kenyans emerged in 1972 from nowhere those performances had roots in 1900s earliest recording sportised event was in 1902 one of first timed events – modern notin of recording

influence from Muscular Christianity through missionaries 1924 bureaucratisation of Kenyan running organised African Olympics records from the 1930s best performance for mile measured to second 1951 formation of African Amateur athletic federation

joy adamson – anthropoligist, research on athletic body, Masai

1954 kenyan began to engage with international comp, NOT 1968 Mexico Olympics

Kenyan Olympics, won medals in high jump, javelin, and sprinting Diversification of athletic production imp At Vancouver Empire Games, team was 2 runners in 440m, 1 in 880m, 1 in 3, 6 miles, … -    no suggestion that this was a running team at all went on into 1960s

present time… -    how does this history help explain Kenyan running? -    Need to take a global perspective -    Can Kenyan running be partly explained by the absence of success in the West -    As West declines in interest in this kind of activity, for various reasons – range of alternative activities, which has led to diminution of people taking part in long distance events. In part, this explains the success of Kenyans. -    There are poor results in these events in the west Has slope in improvement of these records declined? Things are slowing down in those events in the west

Interesting to examine how Kenyans react to this running phenomenon and how Kenyans view the western view of this -    neo-colonialism -    need a Kenyan voice

mtDNA Haplotypes and Demographics f Elite Ethiopian Athletes Robert Scott

Why do some people perform better than others?

Proposed explanations for greater success -    favourable physiology -    altitude adaptation -    running long distances to school -    psychl advantage (and cultural = ME: but actually doesn’t mean this) -    favourable genetic endowment

believes tha genetics is important, but not in way that people have considered

Majority of human genetic diversity is within populations rather than between -    more within East Africa than in Europe

more than skin colour needs to be considered -    ok, so what then?

Ethiopia

Methodology

Enviro analysis -    place of birth -    language -    distance and method of travel to school

genetic analysis: mtDNA -    mitco are major energey producers -    mito function imp in ex

mtDNA useful in population genetics -    maternal inheritance: no recombination -    fast mutation rate (D-loop) -    Maternal ancestry can be traced through branches of tree

MtDNA genome separate from

Buccal swabs from 109 control and 114 elite athletes MtDNA extracted and classifieid -    HVS-1 polymorphism -    Coding region polymorphism

Compare distrib of mtDNA types amongst athletes and controls

Ethiopian Regions -    arsi is over-represented in succeses

Place of birth results

Slightly more from Assis Ababa for elite athletes Large increasee for 18%

Might show that athletics is more prevalent in Arsi

Language Results

Possible that different ethinic goups have different frequencies of gene variant

Might be to do with popularions

Distance travelled to school results

Evidence that this might be influential

Students running some 5-10km to school, and even some running marathon distances.

MtDNA questions -    if mtDNa polymorphisms are imp in endurance performance, will t linage on whch they occur be more common amongst t athletes? -    Might this explain t dominance of East African athletes in distance running?

Contrls’ mtDNA tree -    Mitochondrial Eve

Athletes’ mtDNA tree -    relatively similar distribution -    not significantly different

Conclusions -    Ethiopians are of a distinct enviro background relative to Ethiopian popn -    Athletes have a very deep common maternal ancestry -    Athletes are not a genetically distinct population as defined by mtDNA

How does the ACE I/D polymorphism affect athletic performance, especially in East African athletes? Richard Wilson, Molecular Genetics, IBLS, Glasgow University of Paisley

Why t ACE gene? -    is a major target for blood pressure controlling therapies, and has other less well-understood activities

Why geontype athletes? -    athletes with extremes of physiological performance may help elucidate t physiological variation of normality

why genotype Africans? -    African populations contain more genetic variation than European-derived populations

What does ACE I/D do?

Lots apparaetly -    publications showing effects ranging through, o    – muscle performance in response to training skeletal muscle fibre type (in young Japanese), endurance performance (UK Olympians), high altitude adaptation, survival to 100yrs old (in France); kidney responses, insulin sensitivity, etc

How does ACE (I/D) do all this?

ACE -    activates Angiotensinl to AngiotensinII (which raises blood pressure) -    inactivates Bradykinin (removing a factor which lowers blood pressure) -    Two ACE activities so far, is it all this simple?

ACE is DCP1

ACE is a dipeptidase, cutting two amino acids off peptide hormones -    angiotensiI DRVYIHPF HL -    Bradykinin RPPGFSP – FR -    Haemoregulatory peptide AcSD – KP

Ace is an enxzyme that clips other peptide hormones

High affinity for hameo

Ace is found attached to endothelial cells and soluble in blood plasma Form of ACE is found in sperm -    In mice, where have engineered out sperm type, but not other, sperm no longer functions properly, no longer capable of fertility -    Link to cleaning vaginal secretions, which kill sperm (possible fertility link)

Functional genomics of the human ACE / DCP1 gene -    t full ACE protein has two active sites -    33 ACE isoforms o    som – DCPi – link – DCPi – anchor o    som – DCPi – link I DCPii o    tes – DCPii – anchor (male form)

ACE can do a range of things and is collecticated

Variations in the Human ACE gene -    over 70 common variants (SNPs) in 30000 DNA bases of human ACE Gene -    less than 10 of these ACE SNPs chang t functioning of the ACE gene -    human ACE gene shows t signature of recent natural selection (haplotypes / linkage disequilibrium) -    The famous ACE I/D polymorphism is almost certainly non-functional o    Is in region of gene that is removed

The ACE I/D polymorphism -    is easy to test for -    in Caucasians, ACE I/D is associated with 40% of opulation variation in circulating ACE levels (I low, D high) -    Is ace I/D hitch-hiking with t real functional change? (haplotypes) -    if look for other markers on ACE gene, knowing that how different versions have been shuffled around 22982AG is t best functional candidate, I is always found with 22982A in Caucasians, D with 22982G

DNA sampling at Kaptagat Training camp -    sample using swabs -    can diagnose people’s genotype, to carry out genotyping

An ACE blood sampler -    removed from Kenyan population, -    Kenyan, no longer regulated in same way that they are in Caucasians

ACE I/D PCR -    Extract DNA, and amplify small pieces of it

Can genotype for most markers in the ACE gene -    Roberts and others have set-up assays

ACE activity and I/D -    ethio: 40% variation -    Kenyan: 7%

ACE activity and 22982AG -    real causative agent for circulating ACE levels

Conclusions -    22982AG (not I/D) is t functional polymorphism regulating circulating ACE levels -    Kenyan / African population genetics have modified t assoc between ACE i/D and 22982AG

Few people who came out of africa historically, cold not carry the level of variation that existed in Africa -    expains why we do not see this variance in other locatioes

Is ACE I/D asoc with excelenct in Ethopian -    genotyped 114 (… -    no strong assoc with ACE I/D or 22982AG

Ethiopian ACE/ID data -    not clear that ID is solution for talent searching.

ACE I/D might work differently in males and females

Little effect of ACE ID and other polymorphisms on elite endurance Cannot use it as predictive test, May subtly affect training response Tell everyone they’ve got the ACE gene (placebo effect)!

Any evidence that ACE gene involve with other aspect of performance

Best studies are small groups of people, where have looked at small aspects of physiology , rather than assoc with large athlete cohorts.

Y Chromosome haplotypes and the African endurance Athlete Colin Moran

Overview Existing theories (including genetics) Why Y? -    what is t Y chromosome? -    Y chromosome consortium YCC) tree -    Global distrib

Techniques and subject groups Analysis -    by major clades -    by haplotypes

In the beginning -    Rome Olympics, 1960s -    Atlanta Olympics 1996 -    Sydney Olympics 2000 -    37 of top 40, 10k times

Explanations for Success -    diet -    culture -    genetics o    mtDNA o    ACE o    Alpha-actinin 3 (ACTN3) o    Y chromosome

Now around 100 genes associated with human performance

Human Karyotype -    picture of chromosomes -    23rd ppair of chromosomes are sex chromosomes (smallest) why Y? -    patrilineal inheritance -    never 2 y’s in 1 cell o    functional changes immediately subject to selection o    no recombination

haploid (because only one copy of it)

different types of y chromosome in different proportions around the world, because it is a dynamic chromosome

Summary -    Group analysis: o    Control groups not different o    Some difcs between athlete groups and control groups

-    indiv haplotype anaylsis o    4 haplotypes showed as o    sev haplotypes that we may have expected to showed no assoc •    African specific clades, A and B •    E3b*/E3b4 similar to E3b1 •    J(xJ2) which had apparent

Conclusions -    some Ethiopian Y haplotypes show assoc with elite athletes status, though not really a predictor -    Athletes are more distinct from the Arsi control population than the Addis control o    Arsi control truly representative? •    Town v country?

-    how can t y be having such an effect? o    Direct effect of a gene on the Y chromosome o    Unknown subgroup of the population?

Thanks LeicesterUniversity of Paisley    - mark jobling

Demographic characs of elite Kenyan endurance runners Vincent Ochieng Onywera

The Kenyan Runners: In search of Olympic Glory Mike Boit, Kenyatta University

Olympic boycotts and lack of exposure, performance in Kenya declined significantly

Top runners left or stopped

Kenyan Athletes in top ten of world 1968-72: 1 73-76: 4 77-80: 3 81-84: 1 85-88: 4 89-92: 9 93-96: 6

we are still not at human potential in sport – still not training enough

set backs -    inadequate facilities -    less than minimum sports funding -    lack of sophistication in coaching -    lack of expertise in nutrition -    lack of institutional training -    lack of systematic talent identification plans and implementation programme

CULTURAL traditions -    cattle radigin expedition practices (hugh demand for endurance), suallly taken as sports for the young warriers -    male circumsision (process of instilling high discipline, agresiveness, etc; ability to withstand pain)

would be prudent to assist athletes in providing alternative to taking drugs that could enhance their performance

IOC World Congress on Sport Science (2003, Oct, Athens)

IOC World Congress on Sport Science, Oct, 2003 Genes and Performance Wednesday, 1030am, Chair: Bengt Saltin

Genes and Health Greg collier, AGT Biosciences, LTD, Deakin Uni, International Diabetes Institute and South West foundation Texas

PARL a  new gene involved in muscle function and type 2 diabetes

Literature is full of candidate gene studies – not worth the paper their written on

Unique DNA collection

AGT Biosceince cetre for Stat Genomics

Outbread Israeli Sand Rat Colony

Ezpress Technology Platform

AGT Biosceinces has access to number of human DNA sample collections

Access to unique DNA collections from worldwide populations

Major Collaborators

Dr. John Blangero, Texas -    analysis of genetics of many complex diseases -    devel opf new stat software -    SOLAR

Native habitat is semi-arid regions of middle east

Israeli sand Rat develops diabetes and obesity in manner similar to humans

PARL – Preseneilins-associated rhomboid-like protein

7 transmembrane protein

predicted was located in mitochondria – regulating basic muscle function

Located at chromosome 3q27

Reduced gene expression in muscle of diabetic P. obesus

PARL gene expression was increased after exercise-training

Human gene expression data -    Eric Ravussin, Anthony Civitarese (Pennington Biomedical Research Center)

Discovered by microarrary….

REF: McQuibban, Nature 423, 534 (2003) -    in mitochondria, yeast equivalent…. -    if knock gene out, mitochondria shrink and don’t function correctly

PARL cleaves human equivalent of OPA1… -    in diabetic muscle, where decreased expression of PARL, this is a problem

Mitochondrial defects in genes occur before diabetes occurs

Dgene expression I skeletial musc asso with

REF: Kissebah, AH PNAS 97, 14478 (2000)

Genotyping 50 individuals, XXX

Association studies

Look at relationship of XXX

Responsible for about 5% of variation in insulin levels

Largest yet genetic variation causing insulin resistance

Discovered in muscle of animals

Leu26Val variant of parl asso with plasma insuli, with a strong genotype-by-age variant

Finding genes like this is not simple

Need to combine human linkage studies with expression

Not a worthwhile task to identify a gene and find an association

Brain health, and voluntary running Frank Booth

Epidemiological reports indicate that physically active elderly humans have less cognitive dystnfunction

Laurin Arch Neurol. 58:498, 2001 -    women 65 yars or older, evaluated -    highlevel of phys activ corresponsed to exercise

What is the mechanism? How phys activ tie into brain disfunction

Brain derived neuro..factor (BDNF)

Lu Learn, Mem. 2003, 10: 83-85

Wifdenfalk Neurosci Res 34 125: 1999 -    animals running more had increase in XXX (i.e.

Located in hippocampus -    Hippocampus is highly plastic structure normally asso with cog function, rather than motor

Malcangio Trends Pharmacol Sci 24:116, 2003-10-08

Increase in neurogenesis in hippocampus in animals that are running, compared to animals who are not running

Running primes t brain to enhance neuronal health

It is dogma in medicine that health indivs are the control group and t sick patients are treatment group

It is dogma in exercise that healthy indivs are t treatment group and t sicker population is t control group

Nby calling t phyaically active group t treatment, some others outside of exercise believe that being sedentary is health and thus see no reason to further supp exercise research

Carro, J. Neurosci. 21, 5678, 2001 Carro Mol Neurobi9ol 27, 153, 2003-10-08 -    Increased sendetarism, contributes to an increasing incidence of neurological diseases -    Sedentary life is a risk factor for neurodegenerative disease

What genese are changing in brain that will protect you from neural degeneration

(Saltin: Have identified candidate genes, now how activate?)

Kinetic Consideration of endurance training adaptations Name?

Approx 4 weeks before protein increase, through training

In 1980s, mRNA increase detected after 2 weeks

How do muscle cells adapt to exercise?

Metabolic genes: at transcription or mRNA (transient response)

Measure mRNA increases (transient) 48hrs after exercise – inc in protein concentration

Stress genes Priority Genes Metabolic/Mitochondrial Genes

Adaptations from training have to stem from acute stimulus (exercise bout)

Trying to indicate different categories of genes

Example: PDK4

protoocal after 4 weeks of one-legged knee extensor exercise train

24 hrs after exercise bout, mRNA back to basel levels

during exercise, why would muscle want to shut of a gene that produces carbohydrates? -    hyp: as glucose ….muscle no longer want to use…

Endurance (PGC-1) David Hood, York University, Toronto

Endurance = high capacity of mitochondrial enzyme activity Not only applicable to endurane athletes, but also sedentary individuals – no exercise, low mitochondrial content and endurance capacity)

Ageing and low physical activity, bring mitochon down

Changes in energy status and calcium,. XXXX l

Leads to change of nucleus – transcription factors

Stimuli that affect transcription of nuclear genes

Mitochondria has its own genome -    very limited, only codes for 13 genes (and 100s of genes reqd for mitochondrial function) -    transcription factor for 13 genes is TFAM

Studied with animal model -    chronic stimulation

typical marker for mitochondria (cytochrome C) -    Freyseeenet, et al AJP 277, E26, 1999

Performance change -    muscle force greater fatigue resistance (40% improvement)

PGC-1alpha -    popular due to widespread effects in cell biology -    mediates thyroid -    influ on muscle fibre type -    affects mitochondrial biogenesis

co-activator not a transcrioption factor not binding DNA, but binding transcritpopn factors -    e.g. NRF-1, thyroid receptors (can enhance)

with chronic stim model, looked at PGC-1 level -    nothing happened after 3 days, but by 5, 7, 10, increase in PGC-1 protein by 50% (Irrcher et al AJP 2003, 284)

used cells for better control induce to fuse together -    immature muscle cell. Can make contract, or treat with drug -    not physiological, but useful -    is calcium important in mitochondrial biogenesis

number of transcriptors that could be involved in calcium response -    2.5x inc in PGC-1

effects of exercise on PGC-1 might be mediated by calcium

stimulation model -    cells stimulated in disk -    compared to non stimulated -    looked at factors o    PGC-1 coactives NRF-1 o    NRF-1 transcriptionally activates Tfam and Cyto c) o    Tfam imported to mito and inc mtDNA transcption and copy number o    P38 MAP kinases phosphorylation stablizes PGC-1 protein o    Irrcher et al AJP… (as abobe)

Effect of altering AMPKalpha activity with AICAR -    inc in PGC-1 levels -    which will ultimately affect mito levels

if understand PGC-1, can understand what affects mitochondrial levels

thyroid hormone is another potent stimulator of metabolism -    high thyroid, high mito -    hypo-thyroid is opposite -    also acts by PGC-1

Conclusion

Contractilve activity-endurance signalling of mito bigenesis involves both calcium signals and changed I  ATP turnove and is mediated by PGC-1alpha

Important role of PGC-1 in mataining normal levels…

How neuronal activity controls muscle fiber type and fiber size S. Schiuaffino, Padova

Dissecting signalling pathways involved in activity-dependant muscle gene regulation

Fiber types in skeletal muscle Genetics important, but other factors can modulate fibers -    motorneuron activity is major factor

motorneuron modulate fibre size and fibre type

mechanical effects also important, and one of less explored areas -    sports that generate tension in muiscle (e.g. weightlifting) can induce muscle hypertrophy metabolic changes -    exercise can inc AMP and can activate…?

Try to identify important transaction pathways (activate and block) -    How? o    Pharma not helpful o    Need a genetic approach •    Somatic transgenesis •    Transgenic mice: long procedure •    Instead make transgenic muscles o    Inject foreign DNA through plasmid o    In few days, see effect in muscle phenotype e.g. Changes in MyHC gene expression inducaed by slow motor neuron…

injected mutant  transducers to see if can block effect of nerve or to induce denervated muscle

Murgia et alNature Cell Biol, 2000 Serrano el al PNAS 2001 Pallafaccihna et al PNAS ,2002

Effects: two fibres (injected with foreign DNA) do not express slow myocin

More recently identify transcription factor -    NFAT (transcip factor, protein binding DNA o    Known to translocate o    This translocation been able to….directly, linkd to GFP (fluorescent protein)

Same approach can be used to study muscle hypertrophy

(Saltin: people are on path to find out how performance is regulated)

An overwall enlargement of skeletal muscles is obtained by training and enhanced by anabolic steroids Name? (Female, Paris)

What’s important in skeletal muscle is, as muscle grows, inc proteins, mitochondria, and myonuclei and satellite cells are controlling this

What happens to nuclei in muscle that accompanies growth of muscle fibre As indiv trains (power train), is inc in myonuclear number, and anabolic steroids increase myonuclear number -    amount of cytoplasm remains constant

if inc in no. of nuclei, means that cells have to be added in and must come from myonuclear component

skeletal muscle has cell, reserve cell

satellite cells can proliferate, to allow muscle to grow -    also used to repair muscle

sat cells can be isolated from muscle and grow from biopsy

sat cells isol from human muscle fibres, have ltd capacity to cell

from birth can make 60-70 divisions -    most of these lost during rapid growth

then, muscles stop growing -    from 20-90yrs, maintain capacity to grow and repair skel muscle

Mitotic Clock -    this is why there is a limited capacity, limited by Telemere (on each chromosome, is a piece of redundant DNA, each time cell divides, small part of this DNA will be lost, after while, signals to stop cells from further division, protects cells from cancer, but limits no. times can divide)

in athletes, no. of satellite cells increase on muscle fibre -    to inc muscle mass, to repair muscle

same biopsies – look at telemere length, compared to sedentary -    in elite pro athletes, is small decrease in Tele DNA, muscle is turning over much more than in sedentary population

Athletes with FAMS (Fatigued Athlete Myopathic Syndrome  - Noakes) -    suffering from chronic fatigue -    connective tissue abundant -    inc internal nuclei -    abnormal mito nuclei

compared with control group of sports people

in this syndrome, where overtrain and genetic background, where cannot replenish sat cells, is pathologic – comparable to genetic disease

similar decrease in sat cells in weightlifters with large doping history

lose telemetric DNA each time cell divides

in cell culture, when isolated from elite athletes, compared to sedentary, doing small amount of regular activity is beneficial, because amateurXXXXX? -    what level of activity is beneficial, compared to excessive exercise

Muscle satellite cells activation and skeletal muscle mass recognition Geoff Goldspink

Muscle mass muss be regulated locally and systemically -    must be local growth factors

Alterantive Splicing of Human IGF-1 gene -    now call mechano growth factor (only detected in ?) o    derived from IGF-1 •    IGF-1 genereal growth factor that makes cells inc in size

Normally think of IGF-1 as produced in liver

But MGF has different sequence and different action to systemic factor Activated by chemical signals quickly after exercise?

49 base insert -    ie.  Downstream shifts

put cDNA into different plasmids using same techniqe as earlier paper (inject to muscle of mouse)

made some constructs for in vitro when pt into mouse, found that a group of fibres that hve been tranZZ have inc in size within 2 weeks (25% larger) -    potent growth factor)

how was it doing this? -    looked at cells in culture -    put interest into C2C12 cells o    saw effects of systemic IGF-1, increased in mass, but …?

Subjected rat to mechanical damage, put in myotoxin agent -    to see repair, etc

if look at marker for sat cell activation -    sat cells inc in numbers quickly after injury -    what sort is activating? o    Discovered that shortly after injury MGF is expressed •    Chief contender as major factor activiating sat cells Need to replenish pool of cells, but not too much

Muscles respond to mechanical signals – how? -    not enough sat cells -    seems that they are not activated -    all muscles do not respond to exercise as well, since do not prod enough MGF

(Saltin: now health subject)

Muscle Contraction Febbraio?, Female, Brown hair

Plasma IL-6 -    Ostrowksi et al J. Physiol 1998 -    Ostrowski,

Is IL-6 produced during exercise? -    yes, by working muscles, when it is released into circulation

role of muscle glycogen? -    systemic vs. local effects -    transcription rate inc with exercise, but further enhanced when muscle glycogen is XXX?

What does it mean to feed athletes carbohydrates during exercise? -    IL-6 is inhibited

Febbraio et al 2003

If IL-6 was being produced to signal to liver to produce glucose? -    not clear from findings

Febbraio hiscock, fischer, sachetti, Pederson -    2hrs cycling, at 40% VO2max….etc -    IL-6 can influence glucose production, but co-factor is required

Does IL-6 induce lipolysis? -    yes. Van hall, et al J clin endorcinol metab june 2003-10-08

Keller, FASEB, J, December, XXXX?

Nutrition – supplementation and sports performance

Ergogenic aids:food for performance or food for thought

Diet, training and ergogenic aids: t evidence from antiquity Louis Grivetti

Examples of

Doping Substances in Nutritional Supplements: Results of an IOC study Hans Geyer

Since 1996, Prohormones available over counter

Prohormones of Testosterone -    DHEA

Prohormones of Nandrolone

Labelling of preparations does not reflect actual content

Parasrampuria M. et al 1998

Insufficient urveyence of prohormones

Now analyse  non hormonal

Broad based study of international market

634 nutritional supplements purchased from Oct2000 – Nov 2001

in 13 countries

mainlybourght in shops (91.2%) and internet

289 supplements (49%) from prohorone selling companies

Results: 15% of nutritional supp,ements contained anaboligc androgenic not on label

most of positive nutritional included DHEA andendion

most positive products came from US companies (about 90%!)

do only prohormone companies have positive samples?

10% of products from non pro-hormone also positive

does application of such contamination of substances, lead to positive doping results -    Yes, especially if prohormone of nandrolone

Many victims of contaminated substance? -    Christie, ottie, etc

Conclusion

Problem of non-hormonal nutritional supplements containing prohibited anabolic-androgeneic is international problem

Consumption can lead to positive doping

Minimize risk, athletes should only buy nutritional supplements from companies which perform qualiy check for prohormones that guaranteee

In germany have companies that

www.osp-koeln.de -    low risk suppplments (cannot excp

www.dopinginfo.de

in this study, cases were too low to have a physiological  affect

example from Belgium where athlete has managed to gain compensation from

Muscle Glycogen: train low – compete high

Carbo ingestionduring exercise of longdurationin c performance

High muscle glycogen enhances time to exhaustion

What are infol of CHO ingestion and uiscle glycogen on training??

Training adaptation: what is influ of training at low versus high XXX

Training adaptation -    what is that? -    Molecular mechanisms? o    Accumulation of proteins o    How accumulate protein in muscle?

Prof. Choulis,

Framing it as a problem.

Number of durugs see

Questions

Randy Welberg, USOC presentations

Goldspink - china, factor 8 - haemophilia

International Association for the Philosophy of Sport (2003)

IAPS 2003 Notes Annual meeting, 1030am, sat

Andrew Edgar Sport as Performative Contradiction

Apel, cannot critique ethics, because requires employing an ethical discourse to do so.

Gunnar Brievik Is Base Jumping Morally Justifiable?

Are risk sports valuable, representing  good values?

Method

Present prima facie arguments Intuitive No ethical theory Testby rational analytical tools Bring in some theoretical aspects towards end

Risk sports

High-risk Reckon with possibility of serious injury or death by doing sport Medium risk – may happen, but under unfortunate circumstances Low-risk – almost impossible to get serious injury

Arguments – expense for rescuing jumpers

Should be prohibited? Paternalist: base jumpers do not know what they are doing Moralist: persons are egotistic and selfish

Require 200 jumps from plane before you can jump from a cliff!

If prohibit base jumping, then must prohibit many others

What kind of people are involved in basejumping? -    academics, doctors, family people -    control freaks -    standing at edge: scared to death

Ivo Jirasek Ontology of Experience and Extreme Sports

Friday 1030am TC201 Dewey and competitive

Democracy and community for Dewey are necessarily intertwined

Charlene Weaving The Hooker: analogy between prostitution in sport Julia Roberts in sport Nussbaum: prostitution should be decriminalised -    people against it support inequality

Keith Thompson Sport and Utopia

Henri Rousseau ‘the Footballers’ – Guggenheim NYC -    utopian, since nothing of conflict within it -    they are playing about, not playing o    in Thompson’s utopia, must be the latter

what seems ideal is totally boring -    ideal of completing a round of golf in 18 strokes -    challenge is only a challenge if you can fail to meet it

concept of utopia implodes and we are well rid of it

replace  utopia for intrinsica

Simon Eassom for the IOC, distinction between natural and unnatural is necessary distinction on which the condemnation of technology is based

Ray Williams – Nature problematic concept – Materials of Culture

Nature as absence of man’s influence

We possess a nature and behave according to these ways

HN does not mean that we participate in a nature

We are precisely designating those features.

Notion of our having a nature carries similar …. As saying that animals do not have one

Exclude modes of conduct that do not conform to animal norms

Sport is one remaining arena where natural is threatened by unnatural (e.g. homoerotica)

Authenticity corrupted by cultural progress (unnatural)

Sport schizonphrenic: primativity of play, cyborgian culture

Enlightenment: development of art, science, cult part of project of rediscovering  value of being human

Point is not to return to previous primitivity

Gould vs. Dawkins -    Gould rails human chauvinism in definitions of progress -    Dawkins: progress as tendency to improve human….

Drug user in sport is denaturalised by media, etc

Frankenstein’s monster as ugly

Male athlete not re-sexed by de-sexed Female athlete loses reproductive  integrity

Historicity of nature -    ME: but this is not an argument for rejecting the natural, but rejecting a particular conception of the natural

Andrew Courtwright Objections to Maxim -    could rethink to use: e.g. When I believe my muscle are not getting enough oxygen, will use epo to boost -    motivation for doping: usually a competitive argument, not to get more oxygen to muscles o    ME: not sure I accept this, but even if it is true, if I want to do it for that reason, can I?

Final objection -    Imagine someone faster than anyone else o    If she uses drug, does not seem to be to gain a competitive edge o    Depends on how good an athlete you are

Not surprising that Formula of Universal Law generates these objections

Formula of Humanity -    Treating someone as means not acceptable (Respect for persons argument) -    Treat someone in a way that they cannot consent, not just that they would not consent -    By using PE drugs, are treating other competitors as means o    But: if develop a technique that others do not have. This seems impermissible. But need to distinguish this from doping.

Kingdom of Ends Formula -    indiv agent as part of community of agents -    what sorts of maxims are rationally acceptable to community of agents -    FKE resembles Rawls’ original position

Not all PE drugs are dangerous, but majority are in the way in which athletes use them. Conclusion: Athletes who dope are performing a wrong action. -    Presuming the motivation is to gain a competitive advantage -    modify: athletes who dope, just to gain a competitive advantage, are performing a wrong action.

Doping rules are set up to exclude pharma from sport, while other scientists can make a lot of money

Question: based upon your argument, it would seem that iff the motivation is not to gain a competitive edge and is, perhaps, an expression of our ‘posthumanness’, then you do not wish to prevent me from doing this. The problem is, that is the position of international sport.

Saturday 915am shouler@optonline.net If my life is finite, why am I watching this damned game?

Genetics and Sport (2003, Sept 30, Geneva)

Genes in Sport, Geneva, Sept 30 2003 GATTACA -    crucial point in film where two brothers are swimming against each other and the GM brother says to his brother ‘we cant see the shore, we have to turn back’. This moment is very  interesting because it reveals the relative importance of that contest in comparison to their broader dispute (which was what gave rise to the contest). -    Hero is not merely the ‘natural’ athlete, but also the benevolent and ‘injured’ GM athlete.

Bengt

Bob Goldman (1984) – if take drugs, big success, then death, would you =52% said yes

Lane, T. 2003 Jan A future of jocks, genes and jingoism.  www.theage.com

Veronique L. Bilat Why do Kenyans run so well?

Wolfarth, B. Genes and sports performance: what do we know today, what will we know tomorrow?

GENATHLETE study

ACE and Performance

NOS3 and Performance

Aerobic performance and trainability -    which genes are involved -    what are major intermediate phenotypes for aerobic performance and regulation? -    Poss to predict aerobic performance and trainability levels using genetic markers?

ACEII (not a strong candidate gene) -    cardiac contractility -    cardiac and vascular hypertrophy -    vasoconstriction -    Rigat, B. et al NAR20: 1433, 1992 -    Inertion-/Deletion -    Montgomery, HE Nature (1998) -    ACE in the HERITAGE study o    Cannot support concept that ACE locus plays a contribution to training

No difference between genotypes of trained and untrained athletes, with respect to ACE I/D –polymorphism.

Outside of sport related research (e.g. hypertension), similar findings

ACE I/D also asso with left ventricular hypertrophy -    Landry et al JAMA 1985 254, 1 -    Kupari, 1994, Am J Physio -    Montgomery (1997, Circulation, 96(3) 741-747

Material and Methods LVM (Left ventricular mass)

LVM and LVMI of different ACE I/D genotypes and allele carriers -    any differences between genotypes and carriers? o    No overall association between ACE I/D and LVMI •    But new studies using higher sample o    For carrier status, a small significant difference between I carriers and D carriers •    But I carriers had higher mass (Montgomery concluded that D is responsible for training)

NOS (Nitric oxide synthase) -    REF: McAllister, RM Med Sci sport Exercise, 27 -    Nadaud et al, 1994, -    Nakayama et al 199 – hypertension and left ventric hypertrophy o    Found link between patients with hypertension and left ventric hypertrophy had allele o    Perhaps play a role in endurance o    4 polymorphisms in NOS3 genes analysed o    no different between EEA and SC o    no signif in overall distribution o    but higher proportion for 164 base pair allele •    why? Not sure yet. Might be marker  for variant in surrounding genes, need to screen gene for variants

Perusse, tankinen, Rauramaa, migual rivera, wolfarth, bouchard Human gene map for performance and health related fitness phenotypes: the 2002 update, Med Sci Sport Exercise , Vol 35, no.8

Sandro Rusconi Dept of Medicine, Biochemistry, Uni of Fribourg

Basic understanding of genes -    what is a gene, molecular biology dogma, genetic diseases, environmental factors, ageing

Essential concepts

DNA – RNA - Protein 100000 genes, more than 300000 functions

no such thing as a genetic disease, except for monogenic ones, e.g. muscular dystrophy, where genetic component is dominant

other conditions are significantly environmental and bahvioural -    Familiar breask cncer, poradic breast cancer, lung cancer, obesity, atherosclerosis, alzhiemers, parkinsons, dru abuse, homosexuality

Genes important but cannot define them because they are multi-functional

Science-grade material can be prepared easily Clinical-grade material is more difficult (i.e. GNP prepared vectors for patients) Millilitre of XX is 1franc, for GNP is 10000Francs (safety measures)

Molecular medicine -    prevention, diagnosis, therapy

Four eras of molecular medicine -    eighties: genes as probes (pre-natal diagnosis) -    nineties: genes as factories (isolate gene and put back to work into cells, e.g. yeast, growth factors, pharma products, many of which save lives) -    Y2K: genes as drugs – inject gene into body to correct -    Post-Y2K: post-genomic era

If we live long enough we all get Alzeimers and Cancer! -    these are part of ageing process

Somatic gene transfer

Definition of FT – use of genes as drugs (correcting disorders by somatic gene transfer

Chronic, acute, preventive Hereditary and acquired disorders Loss of function, gain of function

Why somatic? -    somatic gene transfer is a post-natal treatment aiming at somatic cells o    does not led to a hereditary transmission of genetic alteration •    Is not a Genetic selection

Four fundamental questions -    efficiency -    specificity (which kind of tissue to address) -    persistence (acute or rapid treatment) -    toxicity (how toxic is treatment)

Pharmacological considerations

Classical drugs -    synthetically prepared, rapid diffusion,oral delivery poss, cellular delivery, can be delivered as soluble molecules, rapidly reversible treatment

Protein drugs -    e.g EPO -    biggermolecules -    cannot enter into cells -    act exocellary -    if stop using, effect will go away

Nucleic acids -    larger -    biologicall prepared -    slow diffusion -    oral delivery inconceivable -    cellular dlivery: no membrane, no nuclear, no biological import -    must be delvered as complex carrier particles -    slowly or not reversible

therapy with nucleic acids -    reqs particularted -    more complex -    different degrees of reversibility

3 classes of physio gene delivery -    exvivo (bone marrow, liver cells, skin cells) -    invivo (topical delivery) e.g. brain, muscle, eye, joints, tumours) -    invivo (systemic delivery) intravenous,inttra arterial, intra peritoneal o    bigger implications

2 classes of gene transfer -    non viral transfer (transfection) Nuclear envelope barrier, see Nature Biotech, Dec 2001 -    Viral gene transfer (infection)

Popular vectors -    Adenovirus o    No persistence o    Limimited packaging toxicity -    adeno-associated Very -    retrovirus (include. Hiv) o    limited package, random insertion,

Gene Therapy in Clinic -    cancers main

A of Sept 2002, 599 registered protocols, 4000 treated patients -    86% phase I -    13% phase II -    1% phase III

Genetic milestone -    gives overview of recent science -    all experimental

(Road runner cartoon, cayote on drugs)

currently, side effects would and should ethically limit science

3 levels of doping

possible treatments -    Before the competition anabolic enhancers -    During competition – performance enhancers -    After competition – repair enhancers

Anti-TNF factor, BMPs

Current limitations Viral gene transfer (immune problems, limited readmin, gen toxicity Nonviral (inefficient Strategy-indep (laborious, long term different to control, irreversible

Side effects -    short – mid term, autoimmunity, hyperimmunity, toxic shock -    long term: fibrosis cancer, inaccessibility to other interventions

Intrinsic to reckless apliaction (problem biggest danger) -    malpractice (unsuitable vector administration route) -    non-clinical grade material (pathogens or allergens)

Detection -    antibody detection (viral antigens) -    r-nucleic acids

Anatomoically difficult to detect

Need muscle biopsy -    before permit, need strong suspician!

Gene based doping versus drug or protein based doping -    drug protein is most possible -    gene doping detection is difficult or impossible

odds speak against adoption of gene-based doping -    b tu this applies to common-sense clinical practice and this aspect is not guaranteed in doping field

entire  sector of sport where doping is not rigorously controlled

major risk is with premature application

5-10 yrs before effects has been a lot of bad science and Stock market crash has got rid of bad scientist -    follow this up!

Alex Mauron Gene Doping

Ethics of human gene manipulation Convention vs gene doping, ethical differences? Doping and ethics of sport Doping and ethics of human enhancement

Gene therapy: initial ethical debate 1980s -    somatic, and therapeutic OK -    germ-line and enhancement, NOT OK

enhancement is called doping -    not correct: non-medical therapy is characterised as enhancement. That’s all.

1990s many clinical trials of somatic gene therapy, often for polygenic diseases few successes ‘normalisation’ of somatic gene therapy, that is increasingly felt to be similar to any innoivative chemotherapy (paradigm of DNA medicine – A. Kahn) normal doesn’t mean harmless (the Gelsinger case)

Gelsinger case largely misunderstood -    reaction was ‘gene therapy is dangerous’ -    actually, clinical research is dangerous, not just genetics! (whenever system of ethical process breaks down, then it becomes dangerous)

still, messing with genes of humans remains highly controversial. Why?

Genomic metaphysics -    genome represents ontological hardcore of organism, determining both its individuality and species identity -    Mauron, Genomic metaphysics J Mol Biol, 219, 2002 -    Mauron, Is t genome t secular equivalent of soul, science, 2001, 291:831-832

Gene therapy debate concludes that somatic gene therapy is ethically similar to pharma therapy

Same relationship to gene doping and pharma doping

Therefore gene doping would be objectionable on same grounds as doping -    ME: not true: doping is typically associated with anti-social behaviours and a negative sporting culture. Gene doping doesn’t have that context, but if we make it illegal, then we imbue it with that framework

Back to therapy./enhanement distinction

In gene therapy, ethics just as in sport ethics, therapy ok, enhancement is not.

Standard ethics of sport -    let best win -    to bethe best, ought to result from virtuous combintion of innate talent of personal meirt and effort, plus some degree of luck -    chemistry or genetics represent moral shortcuts that substitute undeserved facility where there should be meritorious effort and excellece -    doping disturbs the ‘level playingfield’  need for a fair competition

doping is immemorial -    ME: this is reason to question the moral discourse running through it

Be it through genetics, drugs, or divine intervention, sports has always attracted cheating

Notion of level playing field may be an illusion -    talent: includes genetic differences -    first order capacities (muscultaion potential, bone structure, lung capacity, etc) -    second order capacities (somatopsychic, insentitivity to pain, endurance etc) -    such capacities are unequally distributed almost by definition real reason of prohibition has little to do with fairness, actually has to do with the threat to health of athletes (threatens it more severely than intensive sports training does) -    ME: how do we make this conclusion? -    Well I agree, but this is a partial reading of the situation. Anti-doping is poltically more entrenched than the health issue

What is the merit in sport?

What is merit in scientific training? -    ME: hmmm, it is not easy, as our first presentation indicated

Difference between sports and other competitive human activities -    ME: not sufficient

Our concepts of fairness and merits have been honed by other human activities, and have been applied to sports in appropriately

Conclusion

Enjoy the freaks, Mark Lawson, The Guardian, June 7, 2003.

European College of Sport Science (2003)

ECSS congress Roger Rees victory, violence and values

Rees@adelphi.edu

Ref lessons of the locker room

Game reasoning - bredemeier and shields - moral reasoning in sports more egotistical than everyday life

Playing with pain is part of fair play, but injuring otherwise is not

Norwegian Sport City Program Skille

Sport for All driving policy

Myths of Norway NOC Monopoly, autonomy, and rel bw them and sport for all

Wolfarth, genathlete Do not think that ACE gene has any role in endurance

Msse yearly fitmap update

Heritage study

Animal models

Need to examine other genes

Q. Genetic endowment or trained ability ? - studydoes not take account of trainability, but not convinced that this would be such a wide difc

What about sprinters? - need higher sample size also limit of his study

Shuichi Chakravarthy,J Biol Chem, 2000

How. Does IGF-1 lnfluence p27Kip1 protein IGF-1 inhibit p27Kip1 Forced expression of Fox01 increased p27Kip1 IGF-1 promoted phophorylation of Akt and Fox01 skeletal muscle

Fox01 implicated in aging

Matsakas, myostatin Inhibit  Myostatin promote muscles growth myostatin important for muscles growth through exercise

Volkwein, Distorted Body Image Eating disorders

Technology pushes sporting boundaries (25 March, 2007)

Interview by Australian Associated Press while in Brisbane last week. Here's the outcome:

Technology pushes sporting boundaries

http://tvnz.co.nz/view/page/411366/1035788

Dozens of leading professional golfers, including Tiger Woods, have had eye surgery to improve their vision. Some believe it gives them "better than perfect" eyesight and makes the tricky business of reading greens far easier.

Hundreds of American major league baseball pitchers have had surgery to implant stronger tendons from elsewhere in their bodies into their elbows. Many of them testify that they can throw the ball harder and faster than they could before the operation.

Now the day may not be far away when athletes have microscopic-sized devices implanted in their brains to help them perform better.

According to Dr Andy Miah, a British bioethicist, the line between using technology to improve sporting equipment and using it to improve the bodies of its practitioners is becoming increasingly blurred.

"Sports are technologically enabled practises," Miah said.

"We are pushing the limits of the body technologically and creatively - and I think the relationship between those two is quite close.

"People are fascinated with what the body can do in various kinds of performances."

Miah, who was in Brisbane this week to address a conference organised by the Australian Sports Commission, said functional elective surgery in sport is a more immediate issue than the
long-feared emergence of genetically manipulated athletes.

While the World Anti-Doping Agency concentrates on performance-enhancing drugs and worries about so called "gene-doping", it has no provision in its code for surgically enhanced athletes.

Woods, who was so short-sighted his doctor said he could barely count fingers held in front of his face, wore contact lenses early in his career.

He had laser surgery on his eyes in late 1999. After the surgery, which gave him vision rated at 20-15, Woods said the hole looked bigger to him.

Whether or not the surgery had anything to do with it, Woods won seven of the next eight PGA tour events he played in. The following year he began the "Tiger Slam" in which he became the first man to hold all four Majors at the same time.

Woods' surgeon, Dr Mark Whitten, says the eyesight produced by surgically altering the shape of the cornea gives golfers an enhanced three-dimensional view of the shot confronting them. "It
may be better than normal vision," he says.

Others who have had the surgery include Retief Goosen, Vijay Singh, Scott Hoch, Jesper Parnevik, Lee Westwood and Mike Weir.

Around 10% of major league baseball pitchers in the US have had surgery to strengthen their elbows, which come under enormous strain from repeatedly hurling baseballs at 150 kilometres an hour.

The procedure, called ulnar collateral ligament reconstruction (UCR), is widely know as Tommy John surgery after the pitcher who first had it done in 1974.

According to a report published in USA Today, it involves taking a tendon, usually from the wrist or leg, and grafting it into the elbow in a figure-of-eight pattern through tunnels drilled in the
humerus and ulna bones.

The surgery has saved the careers of hundreds of pitchers, and there is evidence that its success rate is encouraging younger pitchers with only minor elbow injuries to seek the surgery to help their careers.

Some pitchers say they come back better than ever.

"I hit my top speed (in pitch velocity) after the surgery," said Kerry Wood, who had the procedure five years ago and now pitches for the Chicago Cubs. "I'm throwing harder, consistently."

Miah believes there is now a new frontier in sporting technology, driven by the convergence of nanotechnology, biotechnology, information technology and cognitive science.

All of these have profound implications for technological and medical developments generally, as well as within sport.

"It seems likely to me that sports will confront the implications of this convergence quite soon.

"We can imagine nanotechnological devices being utilised by athletes to keep them fit ... these are molecular-sized devices that could be inserted into the brain to elicit certain kinds of
physiological modifications."

The technique has already been used to implant molecular-sized devices into the brains of people suffering from Parkinson's disease.

The implants alter the brain's electrical output to help cure the  uncontrollable shaking that is the main symptom of the disease.

Technology such as this could have implications in shooting, snooker, archery and other disciplines requiring steady aim.

Miah, who believes genetic manipulation of athletes is not necessarily a bad thing, says the march of technology is throwing up some crucial philosophical questions.

"The development of biotechnology, stem cell research, cloning technology and the like has provoked a kind of moral encounter with what it means to be human and what technology might be doing to alter that.

"If we can develop devices that make it difficult to say these are external to the body, if they're implantable into the body then it becomes much harder to say that they are artificial."

The Hastings Center (6-7 December, 2006)

Project meeting where I spoke about the ethics of genetic testing and selecting for enhancement. This work develops ideas that have arisen from a number of recent projects, including the paper I wrote with Emma Rich and my Master degree dissertation in Medical Law. The title of this presentation was 'Is Genetic Selection for Sport a Good idea?'

A link to the presentation powerpoint.

American College of Sports Medicine (30May-3Jun, 2006)

The 42nd Annual meeting of the ACSM takes place in Denver (Colorado) this year. It will be the first ACSM meeting I have attended and I have been invited to be part of a symposium on 'gene doping'. The other panellists include Stephen Roth (Chair, U. of Maryland), Ted Friedmann (WADA), Olivier Rabin (WADA), and Gary Wadler (NYU). It should be an exciting event. 

British Association of Sport and Exercise Medicine (26-27, April 2006)

This month I speak at the spring meeting of BASEM. The title of the event is 'Novel Treatment Approaches in Sports Medicine' (26-27 April, The Belfry, Warwickshire) and I will discuss the related areas of bioethics, science communiation and media studies. Others on the programme include:

Dr Hakan Alfredson on Neovascularisation and its Management

Dr Jacque le Coz on Mesotherapy

Professor Strek on Cryo-Chamber treatment.

The brief for the event is 'to examine the evidence base underpinning some unusual and novel treatment approaches including mesotherapy, actovegan, traumeel, autologous blood injections, hyperbaric oxygen and the current status of stem cell research' The invitation to speak here arose out of a presentation I gave last year for UK Sport. It's great to have a presence on this programme, particularly as it seems to reflect the increasing interest in ethical debates within the biosciences.

Abstract of Presentation

Genetically Modified Athletes?: Bioethics, Science Communication and the Media By Dr Andy Miah, University of Paisley, UK

This paper examines dimensions of ethical debates surrounding novel treatment approaches to sports medicine. It argues that ethical problems must be situated in discussions surrounding science communication, which draw on a critical understanding of media structures. In this context, the paper argues for a ‘public engagement with ethics’ (Miah, 2005a) where this requires consideration of the theoretical and pedagogical foundations of the biosciences and biomedicine.

To explore this thesis, the novel treatment of gene transfer is considered in some depth. The application of gene transfer to elite sports performance has a particularly rich recent history for this purpose. The subject of ‘gene doping’ has generated considerable amounts of debate within ethical, policy and science spheres (Miah, 2004). Moreover, the subject area exists within a recurrent media structure – the prospect of the ‘genetically modified athlete’. To this extent, it is comparable to other major topics in the biomedical sciences, such as human cloning, which similarly has generated recurrent news stories and which also lacks an established evidence base. Questions concerning the ethical issues surrounding novel treatments are of particular relevance given the recent launch of a governmental inquiry into ‘Human Enhancement Technologies in Sport’ (March, 2006). Of particular significance is understanding whether novel treatments can be easily categorised as therapeutic within policy and, if not, what implications this has for their use within elite sport. The paper concludes with some suggestions for informing this inquiring, based on a critique of anti-doping policy (Miah, 2005b).

References

Miah, A. (2004). Genetically Modified Athletes: Biomedical Ethics, Gene Doping and Sport. London and New York, Routledge. Miah, A. (2005a). "Genetics, cyberspace and bioethics: why not a public engagement with ethics?" Public Understanding of Science 14(4): 409-421.

Miah, A. (2005b). "From anti-doping to a 'performance policy': sport technology, being human, and doing ethics." European Journal of Sport Science 5(1): 51-57.

Science and Technology Select Committee (2006, March 1). New Inquiry: Human Enhancement Technologies in Sport. Select Committee for Science and Technology, British Government.

Doping in Torino

I am writing from the Torino Media Centre within the City after having read and heard a lot more about Repoxygen. Over the last few days, there have been a number of journalists getting in touch wanting to find out about this. On Thursday, I interviewed for the Canadian Broadcast Corporation's evening news. I spoke with Tom Harrington, whom I first met in Toronto when Genetically Modified Athletes came out. It's so good to speak to Tom, as he is genuinely interested in the broader philosophical questions that the development in technology provokes. I am also interviewing for CBC's The Hour on Monday, which will take place at the Main Media Centre in Torino. From what I have seen, doping has been high on the news agenda for Torino. There still seems a lot of confusion about whether genetic doping is taking place and there are no confirmed cases. However, there does seem to be a lot of uncertainty about the circumstances here, which is quite different from Athens where nearly no discussions emerged during Games time about whether gene doping might be happening.

From what I have read, there is also less clarity about how best to deal with genetic doping. While WADA and others wish to treat it as just another form of doping, i believe that there is also a philosophical uncertainty about the future of doping and its bearing on humanity. This ambiguity relates to the broader changes within society through technology. In the end, we appear to live within a culture of enhancement and, in this environment, the relevance of prohibiting genetically modified athletes is weakened. All that remains is the medical interest to protect its integrity and the safety of athletes.

If any journalist would like to call me for interview while in Torino, I can be contacted on:

0034 6365 0302

Sport and Medicine, The Lancet

This week, the leading medical journal, The Lancet, Published a special supplement on sport and medicine. Its contents include a number of ethical commentaries including:

Essay: Prosthetics for athletes
McCarvill S
pages S10-S11

Feature: Gene doping
Pincock S
pages S18-S19

Viewpoint: Legalisation of performance-enhancing drugs
Kayser B, Mauron A, Miah A
page S21

Essay: Transsexual athletes—when is competition fair?
Ljungqvist A, Genel M
pages S42-S43

Making Sports Virtual

How long will it be before we ditch the sports arena and compete as athletes - or view as spectators - within an entirely virtual reality? This is the subject of a new book I am writing for The MIT Press, tentatively titled 'CyberSport: Digital Games, Ethics and Cultures'. It will be written with a colleague of mine in Australia, Dr Dennis Hemphill. The subject of this book will feature in a Sky One (television) production to be broadcast on December 2 in the United Kingdom. The programme is about sport and technology generally, and it rounds off with a segment about the prospect of making sports virtual.

This project develops some thoughts that have been hanging around for the last five years. An early example of how they work out can be found in this piece:

Miah, A. (2002) Immersion and Abstraction in Virtual Sport, Research in Philosophy and Technology, 21, 225-233

Andy MIah Sky One Documentary on Digital Technology and Sport (2005, Dec)

"Genetic Technologies Launches Sports Gene Test in Japan"

The launch of the SportsGeneTest in Japan was announced in the Washington Post in mid-September. Here is a quote from the press release: "GTG director, Professor Deon Venter, himself a former British Ironman Triathlon champion, attended the launch. Professor Venter commented, "Japan represents a significant market for the ACTN3 SportsGene Test(TM), with highly influential sporting and government bodies keen to explore the relationship between genetics and sporting performance. Japan is an extremely technologically-sophisticated country and is now taking a leadership position in the science of optimizing a person's sports potential according to their inherited genetic capabilities."

Doping & the Child

In April this year, I published a brief commentary about the American Academy of Pediatrics statement on performance-enhancing drugs in sport. This commentary was extended and published in the Sept 10 issue of The Lancet. Full reference as follows: Miah, A. (2005, Sept 10). "Doping and the child: an ethical policy for the vulnerable." The Lancet 366: 874-876.